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• W2024143956 startingPage "2585" @default.
• W2024143956 abstract "Feline immunodeficiency virus (FIV) infection in cats is associated with an increase of feline CD (fCD)8 α + β − and fCD8 α + β low cells in peripheral blood. To investigate these cells in more detail, an anti-fCD3 ε mAb, termed NZM1, was generated, which recognizes the extracellular epitope of the fCD3 ε molecule. The anti-fCD3 ε mAb proved to be more suitable for identifying feline T cells than the anti-fCD5 one, which has been used as a pan-T-cell reagent in cats, because of the presence of fCD5 + fCD3 ε − cells among lymphocytes. Although the fCD8 α + β − and fCD8 α + β low cells in the FIV-infected cats expressed fCD3 ε , a subset of fCD8 α + β − cells expressed fCD3 ε antigen at a lower level than the T cells whose phenotype was fCD4 + , or fCD8 α + β low . The lower expression of fCD3 ε may be associated with the immune status of fCD8 α + β − T cells." @default.
• W2024143956 created "2016-06-24" @default.
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• W2024143956 date "2004-09-01" @default.
• W2024143956 modified "2023-10-16" @default.
• W2024143956 title "Downmodulation of CD3ε expression in CD8α + β − T cells of feline immunodeficiency virus-infected cats" @default.
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• W2024143956 doi "https://doi.org/10.1099/vir.0.80102-0" @default.
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