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- W2024150888 abstract "It is increasingly likely that non‐cardiac‐related drugs will need to be routinely analyzed for their ability to prolong cardiac repolarization. This leads to potential problems for drug companies in general and statisticians in particular. A number of issues immediately arise in regard to answering the question, “Does drug X prolong cardiac repolarization?” These include identifying what is the desired outcome, what is the dependent variable, and what analysis method should be used. The purpose of this article is bring to to light some of the issues regarding the analysis of QTc data, the advantages and disadvantages of these analysis methods, and some general recommendations." @default.
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- W2024150888 title "Assessment of QTc Prolongation for Non‐Cardiac‐Related Drugs from a Drug Development Perspective" @default.
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- W2024150888 doi "https://doi.org/10.1177/00912709922007912" @default.
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