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- W2024159265 abstract "The in situ uptake from the rat jejunum of liposomes prepared from various saturated phosphatidylcholines in the presence or absence of cholesterol was determined. Liposomes prepared from distearoylphosphatidylcholine, with or without cholesterol, were taken up at the fastest rate (apparent first-order uptake of intact liposomes with a half-life of about 15 min). The lipid components of liposomes could not be found in compartments where liposomes would be expected to accumulate, i.e. liver, spleen, lymph nodes, or thoracic lymphatic duct. Furthermore, inulin, when encapsulated in the liposomes, could not be found in the urine. When either PEG-4000 (a non-absorbable marker) or glucose (an absorbable marker) was entrapped within the liposome, all of the liposomes and markers that were taken up still remained associated with the jejunum and the liposomes remained intact." @default.
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- W2024159265 date "1984-01-01" @default.
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- W2024159265 title "In situ jejunal uptake from liposomal systems" @default.
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