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• W2024165183 abstract "Significance Regulation of differential gene expression by Wnt/glycogen synthase kinase 3 (GSK3) signaling plays a major role in development, but there is accumulating evidence for a transcription-independent function of this pathway. In mature oocytes and early embryos, transcription is temporarily silenced, providing an opportunity to study the nontranscriptional role of Wnt signaling. Our study shows that inhibition of Wnt signaling in frog oocytes leads to early cleavage arrest after fertilization and provides evidence that this process occurs by regulating proteins involved in mitosis. Our study indicates that control of early development is a prominent role for nontranscriptional, Wnt/GSK3 signaling." @default.
• W2024165183 created "2016-06-24" @default.
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• W2024165183 date "2015-04-21" @default.
• W2024165183 modified "2023-10-10" @default.
• W2024165183 title "Maternal Wnt/STOP signaling promotes cell division during early <i>Xenopus</i> embryogenesis" @default.
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• W2024165183 doi "https://doi.org/10.1073/pnas.1423533112" @default.
• W2024165183 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4426427" @default.
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