FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024169013> ?p ?o ?g. }

• W2024169013 endingPage "285" @default.
• W2024169013 startingPage "271" @default.
• W2024169013 abstract "The development of adenylate cyclase responsiveness to vasopressin and parathyroid hormone was studied using membrane fractions prepared from medullo-papillary and cortical portions of kidneys of 2–46-day-old rats. The development of vasopressin binding capacity was followed on the same preparations, using [3H] vasopressin. The characteristics of medullo-papillary adenylate cyclase response to vasopressin were identical in young and adult control animals as regards apparent Km values for [Lys8]vasopressin (3 × 10−8 M), specificity towards the natural neurohypophysial peptides and the effects of Mg2+. However, the magnitude of maximal enzyme activation by vasopressin was much lower in very young than adult animals. Accordingly vasopressin responsiveness increased sharply between the 10th and 25th days but the magnitude of the maximal response only reached the adult value between the 30th and 45th days after birth. During both periods basal adenylate cyclase activity was almost independent of age. Specific vasopressin binding sites were detected on kidney medullo-papillary membranes from young animals. Vasopressin binding capacity and adenylate cyclase responsiveness to the hormone followed similar development patterns. However, the appearance of specific binding sites slightly preceded the onset of adenylate cyclase responsiveness. Basal cortical adenylate cyclase activity/mg protein was 12 times higher in 2-day-old rats than in the adult controls. It dropped with age but only fell to the adult value between the 25th and the 35th days after birth. For the youngest animals tested (2 days old), the increase in activity due to parathyroid hormone was about half the increase measured in adults, and gradually rose to about 75% of the adult response between the 2nd and 46th days after birth. Apparent Km values for parathyroid hormone were identical in young and adult animals (3.2 and 3.0 U/ml, respectively)." @default.
• W2024169013 created "2016-06-24" @default.
• W2024169013 creator A5034812092 @default.
• W2024169013 creator A5056271124 @default.
• W2024169013 creator A5086271349 @default.
• W2024169013 date "1976-03-01" @default.
• W2024169013 modified "2023-10-15" @default.
• W2024169013 title "Ontogenic development of antidiuretic hormone receptors in rat kidney: Comparison of hormonal binding and adenylate cyclase activation" @default.
• W2024169013 cites W1500214274 @default.
• W2024169013 cites W1592059338 @default.
• W2024169013 cites W1599995112 @default.
• W2024169013 cites W1609280109 @default.
• W2024169013 cites W1775749144 @default.
• W2024169013 cites W1965853065 @default.
• W2024169013 cites W1968480656 @default.
• W2024169013 cites W1972223258 @default.
• W2024169013 cites W1997154419 @default.
• W2024169013 cites W1998616639 @default.
• W2024169013 cites W2001628149 @default.
• W2024169013 cites W2008447248 @default.
• W2024169013 cites W2011125672 @default.
• W2024169013 cites W2027314841 @default.
• W2024169013 cites W2053640165 @default.
• W2024169013 cites W2055383210 @default.
• W2024169013 cites W2061189958 @default.
• W2024169013 cites W2064327350 @default.
• W2024169013 cites W2065813261 @default.
• W2024169013 cites W2069986440 @default.
• W2024169013 cites W2070505004 @default.
• W2024169013 cites W2094668162 @default.
• W2024169013 cites W2095423633 @default.
• W2024169013 cites W2142419843 @default.
• W2024169013 cites W2151118695 @default.
• W2024169013 cites W2329073995 @default.
• W2024169013 cites W2356432090 @default.
• W2024169013 cites W2419157535 @default.
• W2024169013 doi "https://doi.org/10.1016/0303-7207(76)90061-7" @default.
• W2024169013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/177322" @default.
• W2024169013 hasPublicationYear "1976" @default.
• W2024169013 type Work @default.
• W2024169013 sameAs 2024169013 @default.
• W2024169013 citedByCount "82" @default.
• W2024169013 countsByYear W20241690132013 @default.
• W2024169013 countsByYear W20241690132014 @default.
• W2024169013 countsByYear W20241690132015 @default.
• W2024169013 countsByYear W20241690132016 @default.
• W2024169013 countsByYear W20241690132017 @default.
• W2024169013 countsByYear W20241690132019 @default.
• W2024169013 countsByYear W20241690132021 @default.
• W2024169013 countsByYear W20241690132022 @default.
• W2024169013 countsByYear W20241690132023 @default.
• W2024169013 crossrefType "journal-article" @default.
• W2024169013 hasAuthorship W2024169013A5034812092 @default.
• W2024169013 hasAuthorship W2024169013A5056271124 @default.
• W2024169013 hasAuthorship W2024169013A5086271349 @default.
• W2024169013 hasConcept C126322002 @default.
• W2024169013 hasConcept C134018914 @default.
• W2024169013 hasConcept C170493617 @default.
• W2024169013 hasConcept C180526460 @default.
• W2024169013 hasConcept C185592680 @default.
• W2024169013 hasConcept C24998067 @default.
• W2024169013 hasConcept C2776370428 @default.
• W2024169013 hasConcept C2776885963 @default.
• W2024169013 hasConcept C2778024521 @default.
• W2024169013 hasConcept C2779306644 @default.
• W2024169013 hasConcept C2780069284 @default.
• W2024169013 hasConcept C2781208988 @default.
• W2024169013 hasConcept C519063684 @default.
• W2024169013 hasConcept C71315377 @default.
• W2024169013 hasConcept C71924100 @default.
• W2024169013 hasConcept C86803240 @default.
• W2024169013 hasConcept C90474776 @default.
• W2024169013 hasConceptScore W2024169013C126322002 @default.
• W2024169013 hasConceptScore W2024169013C134018914 @default.
• W2024169013 hasConceptScore W2024169013C170493617 @default.
• W2024169013 hasConceptScore W2024169013C180526460 @default.
• W2024169013 hasConceptScore W2024169013C185592680 @default.
• W2024169013 hasConceptScore W2024169013C24998067 @default.
• W2024169013 hasConceptScore W2024169013C2776370428 @default.
• W2024169013 hasConceptScore W2024169013C2776885963 @default.
• W2024169013 hasConceptScore W2024169013C2778024521 @default.
• W2024169013 hasConceptScore W2024169013C2779306644 @default.
• W2024169013 hasConceptScore W2024169013C2780069284 @default.
• W2024169013 hasConceptScore W2024169013C2781208988 @default.
• W2024169013 hasConceptScore W2024169013C519063684 @default.
• W2024169013 hasConceptScore W2024169013C71315377 @default.
• W2024169013 hasConceptScore W2024169013C71924100 @default.
• W2024169013 hasConceptScore W2024169013C86803240 @default.
• W2024169013 hasConceptScore W2024169013C90474776 @default.
• W2024169013 hasIssue "4" @default.
• W2024169013 hasLocation W20241690131 @default.
• W2024169013 hasLocation W20241690132 @default.
• W2024169013 hasOpenAccess W2024169013 @default.
• W2024169013 hasPrimaryLocation W20241690131 @default.
• W2024169013 hasRelatedWork W124728163 @default.
• W2024169013 hasRelatedWork W1578076358 @default.
• W2024169013 hasRelatedWork W180243494 @default.
• W2024169013 hasRelatedWork W1964888906 @default.

• next