FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024170846> ?p ?o ?g. }

• W2024170846 endingPage "10" @default.
• W2024170846 startingPage "6" @default.
• W2024170846 abstract "The aim of this study was to analyse how the results of Gram-staining vaginal smears correlated with the clinical criteria for determining the existence of bacterial vaginosis (BV) and, in particular, how the category defined as 'intermediate' or Gram grade II did so and its significance. Women attending an antenatal clinic with an abnormal vaginal flora, that is those who had Gram-stains of grades II or III, the latter considered to equate with BV, were given clindamycin or a placebo intravaginally and examined again on up to three occasions. Gram-stain readings of grade III correlated with the clinical criteria for BV on 356 (91.7%) of 388 occasions. Grade II readings covered the spectrum of clinical criteria and correlated with those for BV on 35 (37.2%) of 94 occasions. Grade I, recorded 231 times and seen usually after clindamycin treatment, was associated with BV only once. The sensitivity, specificity, positive predictive value and negative predictive value of the Gram stain for the diagnosis of BV, based on a combination of grades II and III, were 99.7%, 71.6%, 81% and 99.6%, respectively; based on grade III only, the values were 99.7%, 87.7%, 91.6% and 99.6%, respectively. Women reported a malodorous vaginal discharge on 49.2% of the occasions a grade III flora was seen and 13.3% of the times grade II was recorded. It was not associated with grade I and would seem a useful adjunct to the accepted clinical criteria for diagnosing BV. Each of the clinical criteria was found in about equal proportions (87%-91%) for women whose Gram grade was III. For grade II, an increased discharge was noted most often (76.5%) and 'clue' cells least often (24.5%). A positive amine test was the most specific, being associated with <1% of grade I smears. Of women with grade III status, 91% reverted to grade I after treatment with clindamycin for three days. In contrast, of women with grade II status, 53% reverted to grade I, as did 47% of those who were given a placebo. The 'intermediate' (grade II) category is a Gram-stain diagnosis and not one that can be made clinically. It is important to recognize as a distinct entity not only because amalgamation with grade III diminishes the specificity and positive predictive value of the Gram-stain for diagnosing BV, but also because women of grade II status usually fail to respond to clindamycin treatment, whereas those of grade III do not." @default.
• W2024170846 created "2016-06-24" @default.
• W2024170846 creator A5019674085 @default.
• W2024170846 creator A5020202309 @default.
• W2024170846 creator A5030109089 @default.
• W2024170846 creator A5037187497 @default.
• W2024170846 creator A5063092455 @default.
• W2024170846 date "2003-01-01" @default.
• W2024170846 modified "2023-09-27" @default.
• W2024170846 title "Relation between Gram-stain and clinical criteria for diagnosing bacterial vaginosis with special reference to Gram grade II evaluation" @default.
• W2024170846 doi "https://doi.org/10.1258/095646203321043183" @default.
• W2024170846 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12590785" @default.
• W2024170846 hasPublicationYear "2003" @default.
• W2024170846 type Work @default.
• W2024170846 sameAs 2024170846 @default.
• W2024170846 citedByCount "34" @default.
• W2024170846 countsByYear W20241708462013 @default.
• W2024170846 countsByYear W20241708462014 @default.
• W2024170846 countsByYear W20241708462015 @default.
• W2024170846 countsByYear W20241708462016 @default.
• W2024170846 countsByYear W20241708462018 @default.
• W2024170846 countsByYear W20241708462020 @default.
• W2024170846 countsByYear W20241708462022 @default.
• W2024170846 countsByYear W20241708462023 @default.
• W2024170846 crossrefType "journal-article" @default.
• W2024170846 hasAuthorship W2024170846A5019674085 @default.
• W2024170846 hasAuthorship W2024170846A5020202309 @default.
• W2024170846 hasAuthorship W2024170846A5030109089 @default.
• W2024170846 hasAuthorship W2024170846A5037187497 @default.
• W2024170846 hasAuthorship W2024170846A5063092455 @default.
• W2024170846 hasConcept C126322002 @default.
• W2024170846 hasConcept C141071460 @default.
• W2024170846 hasConcept C142724271 @default.
• W2024170846 hasConcept C161369605 @default.
• W2024170846 hasConcept C204787440 @default.
• W2024170846 hasConcept C205501099 @default.
• W2024170846 hasConcept C27081682 @default.
• W2024170846 hasConcept C2776393945 @default.
• W2024170846 hasConcept C2777458120 @default.
• W2024170846 hasConcept C2777700855 @default.
• W2024170846 hasConcept C2777744392 @default.
• W2024170846 hasConcept C2777831542 @default.
• W2024170846 hasConcept C2779952448 @default.
• W2024170846 hasConcept C29456083 @default.
• W2024170846 hasConcept C3019719930 @default.
• W2024170846 hasConcept C501593827 @default.
• W2024170846 hasConcept C523546767 @default.
• W2024170846 hasConcept C54355233 @default.
• W2024170846 hasConcept C71924100 @default.
• W2024170846 hasConcept C86803240 @default.
• W2024170846 hasConcept C89423630 @default.
• W2024170846 hasConcept C90924648 @default.
• W2024170846 hasConceptScore W2024170846C126322002 @default.
• W2024170846 hasConceptScore W2024170846C141071460 @default.
• W2024170846 hasConceptScore W2024170846C142724271 @default.
• W2024170846 hasConceptScore W2024170846C161369605 @default.
• W2024170846 hasConceptScore W2024170846C204787440 @default.
• W2024170846 hasConceptScore W2024170846C205501099 @default.
• W2024170846 hasConceptScore W2024170846C27081682 @default.
• W2024170846 hasConceptScore W2024170846C2776393945 @default.
• W2024170846 hasConceptScore W2024170846C2777458120 @default.
• W2024170846 hasConceptScore W2024170846C2777700855 @default.
• W2024170846 hasConceptScore W2024170846C2777744392 @default.
• W2024170846 hasConceptScore W2024170846C2777831542 @default.
• W2024170846 hasConceptScore W2024170846C2779952448 @default.
• W2024170846 hasConceptScore W2024170846C29456083 @default.
• W2024170846 hasConceptScore W2024170846C3019719930 @default.
• W2024170846 hasConceptScore W2024170846C501593827 @default.
• W2024170846 hasConceptScore W2024170846C523546767 @default.
• W2024170846 hasConceptScore W2024170846C54355233 @default.
• W2024170846 hasConceptScore W2024170846C71924100 @default.
• W2024170846 hasConceptScore W2024170846C86803240 @default.
• W2024170846 hasConceptScore W2024170846C89423630 @default.
• W2024170846 hasConceptScore W2024170846C90924648 @default.
• W2024170846 hasIssue "1" @default.
• W2024170846 hasLocation W20241708461 @default.
• W2024170846 hasLocation W20241708462 @default.
• W2024170846 hasOpenAccess W2024170846 @default.
• W2024170846 hasPrimaryLocation W20241708461 @default.
• W2024170846 hasRelatedWork W1010293186 @default.
• W2024170846 hasRelatedWork W1636224414 @default.
• W2024170846 hasRelatedWork W2005248990 @default.
• W2024170846 hasRelatedWork W2009440331 @default.
• W2024170846 hasRelatedWork W2024170846 @default.
• W2024170846 hasRelatedWork W2052984275 @default.
• W2024170846 hasRelatedWork W2139137497 @default.
• W2024170846 hasRelatedWork W4242233470 @default.
• W2024170846 hasRelatedWork W4309416584 @default.
• W2024170846 hasRelatedWork W4367336535 @default.
• W2024170846 hasVolume "14" @default.
• W2024170846 isParatext "false" @default.
• W2024170846 isRetracted "false" @default.
• W2024170846 magId "2024170846" @default.
• W2024170846 workType "article" @default.