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- W2024174974 abstract "Autoimmunity directed against retinal or choroidal antigens has been suggested to play a role in the chorioretinal lesions observed in patients with Fuchs9 heterochromic cyclitis. This hypothesis was addressed and patients with Fuchs9 heterochromic cyclitis were tested for cellular immunity (migration inhibitory factor assay) against human retinal S-antigen. A significantly higher percentage of patients with Fuchs9 heterochromic cyclitis had a positive cellular autoimmune response to S-antigen than healthy controls and other patients with anterior uveitis. This finding is remarkable since Fuchs9 heterochromic cyclitis is generally classified as an anterior uveitis and patients with Fuchs9 heterochromic cyclitis without chorioretinal lesions also had a positive test. In view of these results and a sensitisation against a corneal antigen reported earlier in Fuchs9 heterochromic cyclitis, it is suggested that a chronic low grade grade anterior uveitis or chorioretinitis of unknown origin may cause the release of potent autoantigens in these patients." @default.
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- W2024174974 title "Does autoimmunity to S-antigen play a role in Fuchs' heterochromic cyclitis?" @default.
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- W2024174974 doi "https://doi.org/10.1136/bjo.77.7.436" @default.
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