FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024185461> ?p ?o ?g. }

• W2024185461 endingPage "528" @default.
• W2024185461 startingPage "521" @default.
• W2024185461 abstract "Sympathetic nervous system hyperactivity is observed in patients with renal injury, renovascular hypertension, chronic kidney disease (CKD) and end-stage renal disease (ESRD). Elevated sympathetic activity is of prognostic relevance in that plasma norepinephrine concentrations predict survival and the incidence of cardiovascular events in patients with ESRD, as well as future renal injury in normotensive healthy subjects with renal function in the normal range. Renal injury, CKD and ESRD are often associated with obesity, and its common sequelae hypertension and diabetes. In fact, hypertension and diabetes mellitus are the main causes of ESRD in western societies and together account for approximately more than 50% of ESRD incidence in the United States and Japan. Obesity also leads to increases in the incidence of cardiovascular diseases. Several clinical and epidemiological studies have clearly documented that heightened sympathetic nervous activity has an important role in the onset and maintenance of obesity and hypertension. Elevated sympathetic nervous activity may actually represent an important mechanism contributing to the onset and maintenance of renal injury at least in part through its concomitant adverse effects on obesity and hypertension. Understanding the contribution of sympathetic nervous hyperactivity to the onset and maintenance of renal injury might aid in the prevention and treatment of renal injury, CKD and ESRD. Very recently, renal sympathetic denervation was shown to be a potentially novel therapeutic strategy in resistant hypertension. In addition, renin-angiotensin system inhibitors are recommended as the initial therapy because of their renal protective effect, especially in hypertensive patients with type 2 diabetes or with proteinuria. The purpose of this review is to provide an overview of our current knowledge on the relationships between sympathetic nerve activity and renal function to further our understanding of the precise roles of sympathetic nerve activity in renal injury, particularly in the context of obesity and hypertension. These insights may be useful to improve prevention and treatment of renal injury in these patients." @default.
• W2024185461 created "2016-06-24" @default.
• W2024185461 creator A5011375886 @default.
• W2024185461 creator A5021267745 @default.
• W2024185461 creator A5047370873 @default.
• W2024185461 creator A5069785747 @default.
• W2024185461 creator A5078822609 @default.
• W2024185461 creator A5086606783 @default.
• W2024185461 date "2010-03-26" @default.
• W2024185461 modified "2023-10-10" @default.
• W2024185461 title "The role of sympathetic nervous activity in renal injury and end-stage renal disease" @default.
• W2024185461 cites W1525805187 @default.
• W2024185461 cites W1581149420 @default.
• W2024185461 cites W1964227153 @default.
• W2024185461 cites W1964583269 @default.
• W2024185461 cites W1967340565 @default.
• W2024185461 cites W1967944474 @default.
• W2024185461 cites W1969748795 @default.
• W2024185461 cites W1970706622 @default.
• W2024185461 cites W1973272652 @default.
• W2024185461 cites W1976286624 @default.
• W2024185461 cites W1976289196 @default.
• W2024185461 cites W1977607782 @default.
• W2024185461 cites W1980617545 @default.
• W2024185461 cites W1987047246 @default.
• W2024185461 cites W1992273900 @default.
• W2024185461 cites W1993104550 @default.
• W2024185461 cites W1998810366 @default.
• W2024185461 cites W2002932114 @default.
• W2024185461 cites W2005605175 @default.
• W2024185461 cites W2012143854 @default.
• W2024185461 cites W2012968926 @default.
• W2024185461 cites W2013332206 @default.
• W2024185461 cites W2015155834 @default.
• W2024185461 cites W2018796965 @default.
• W2024185461 cites W2029727332 @default.
• W2024185461 cites W2031077437 @default.
• W2024185461 cites W2032604470 @default.
• W2024185461 cites W2035576585 @default.
• W2024185461 cites W2036689966 @default.
• W2024185461 cites W2037966740 @default.
• W2024185461 cites W2038408757 @default.
• W2024185461 cites W2040834753 @default.
• W2024185461 cites W2047501896 @default.
• W2024185461 cites W2049525976 @default.
• W2024185461 cites W2049739776 @default.
• W2024185461 cites W2052658828 @default.
• W2024185461 cites W2054310260 @default.
• W2024185461 cites W2072301703 @default.
• W2024185461 cites W2079079593 @default.
• W2024185461 cites W2082033318 @default.
• W2024185461 cites W2091142003 @default.
• W2024185461 cites W2091856082 @default.
• W2024185461 cites W2098616191 @default.
• W2024185461 cites W2099737510 @default.
• W2024185461 cites W2101464945 @default.
• W2024185461 cites W2102175643 @default.
• W2024185461 cites W2107144085 @default.
• W2024185461 cites W2109625017 @default.
• W2024185461 cites W2115461708 @default.
• W2024185461 cites W2118825573 @default.
• W2024185461 cites W2119686163 @default.
• W2024185461 cites W2122796015 @default.
• W2024185461 cites W2131490804 @default.
• W2024185461 cites W2134037156 @default.
• W2024185461 cites W2135980304 @default.
• W2024185461 cites W2146835687 @default.
• W2024185461 cites W2147464692 @default.
• W2024185461 cites W2148758500 @default.
• W2024185461 cites W2149376469 @default.
• W2024185461 cites W2149561396 @default.
• W2024185461 cites W2150333966 @default.
• W2024185461 cites W2155961397 @default.
• W2024185461 cites W2157131266 @default.
• W2024185461 cites W2162713300 @default.
• W2024185461 cites W2166904705 @default.
• W2024185461 cites W2171788381 @default.
• W2024185461 cites W2189612961 @default.
• W2024185461 cites W2323009138 @default.
• W2024185461 cites W2338638760 @default.
• W2024185461 cites W4256587543 @default.
• W2024185461 cites W4362107861 @default.
• W2024185461 doi "https://doi.org/10.1038/hr.2010.35" @default.
• W2024185461 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20339374" @default.
• W2024185461 hasPublicationYear "2010" @default.
• W2024185461 type Work @default.
• W2024185461 sameAs 2024185461 @default.
• W2024185461 citedByCount "87" @default.
• W2024185461 countsByYear W20241854612012 @default.
• W2024185461 countsByYear W20241854612013 @default.
• W2024185461 countsByYear W20241854612014 @default.
• W2024185461 countsByYear W20241854612015 @default.
• W2024185461 countsByYear W20241854612016 @default.
• W2024185461 countsByYear W20241854612017 @default.
• W2024185461 countsByYear W20241854612018 @default.
• W2024185461 countsByYear W20241854612019 @default.
• W2024185461 countsByYear W20241854612020 @default.
• W2024185461 countsByYear W20241854612021 @default.

• next