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- W2024187848 abstract "Gangliosides that contain the disialosyl residue α-Neu5Ac-(2→8)-α-Neu5Ac-(2→3)- can lactonize in the presence of traces of acid and this reaction has been studied in detail on GD1b {β-Gal-(1→3)-β-GalNAc-(1→4)-[α-Neu5Ac-(2→8)-α-Neu5Ac-(2→3)]-β-Gal-(1→4)-β-Glc-(1→1)-Cer}. Lactonization occurs rapidly at a proton-ganglioside molar ratio of ⪢1. At equilibrium, the ratio of GD1b to its lactone is 3:7. The data suggest the possibility that a proton-driven lactonization of gangliosides may occur in vivo." @default.
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- W2024187848 date "1989-10-01" @default.
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- W2024187848 title "Lactonization of GD1b ganglioside under acidic conditions" @default.
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- W2024187848 doi "https://doi.org/10.1016/0008-6215(89)85113-4" @default.
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