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- W2024189377 abstract "Proteolysis within the cardiac sarcomere is a constantly evolving area of research. Three major pathways of proteolysis have been identified as being active within the cardiac sarcomere, namely the ubiquitin-proteasome system, autophagy, and the calpain system. The role of ubiquitin-proteasome system-mediated proteolysis in cardiovascular health and disease has been known for some time; however, it is now apparent that other proteolytic systems also aid in the stabilization of cardiac sarcomere structure and function. This minireview focuses on the individual as well as cooperative involvement of each of these three major pathways of proteolysis within the cardiac sarcomere." @default.
- W2024189377 created "2016-06-24" @default.
- W2024189377 creator A5028997082 @default.
- W2024189377 creator A5044287395 @default.
- W2024189377 creator A5077459772 @default.
- W2024189377 date "2011-03-01" @default.
- W2024189377 modified "2023-10-13" @default.
- W2024189377 title "Tearin' Up My Heart: Proteolysis in the Cardiac Sarcomere" @default.
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- W2024189377 doi "https://doi.org/10.1074/jbc.r110.170571" @default.
- W2024189377 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3060546" @default.
- W2024189377 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21257759" @default.
- W2024189377 hasPublicationYear "2011" @default.
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