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- W2024190667 abstract "We investigated the effect of small cortical ischemic lesions, produced by intracerebral injection of the vasoconstrictor endothelin-1, on neurogenesis in the adult mouse subventricular zone. Endothelin-1 (0.5–1 μg) produced infarcts restricted to the cortex, and associated neurobehavioral deficits that largely resolved by 3 days. Bromodeoxyuridine labeling of proliferating cells in the subventricular zone was elevated by about 50% in endothelin-1-treated mice, and cells reactive for doublecortin, a marker for immature neurons, were similarly increased in number. These findings indicate that small ischemic lesions restricted to adult cerebral cortex can stimulate neuroproliferation at a distance." @default.
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- W2024190667 date "2007-09-01" @default.
- W2024190667 modified "2023-10-04" @default.
- W2024190667 title "Neurogenesis associated with endothelin-induced cortical infarction in the mouse" @default.
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- W2024190667 doi "https://doi.org/10.1016/j.brainres.2007.06.065" @default.
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