Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024192457> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2024192457 abstract "Abstract Human peripheral blood lymphocytes (PBL) were depleted and enriched for natural killer target-binding cells (NK-TBC) by sedimentation of MOLT 4 tumor conjugate suspensions over discontinuous gradients. NK-TBC-depleted PBL consistently demonstrated diminished NK cytolytic levels whereas the NK levels of PBL enriched for NK-TBC were at least six-to eight-fold greater. An equal ratio of NK-TBC-enriched and depleted PBL combined at the time of cytotoxicity assay demonstrated NK levels intermediate between those of TBC-enriched and depleted PBL. However, coculturing NK-TBC-enriched and depleted PBL for 18 hr resulted in levels equivalent to those of NK-TBC-enriched cells and greater than those predicted from either population cultured alone. The increased NK activity in 18-hr cocultures required protein synthesis by TBC-enriched cells but was not abrogated by anti-interferon antibodies. In other experiments both NK-TBC-depleted and -enriched populations demonstrated considerable NK activity after exposure to autologous non-T lymphocytes. Also, autologous monocytes were found to inhibit the generation of NK activity among TBC-depleted PBL exposed to autologous non-T lymphocytes. The results suggest that non-TBC PBL have the potential to develop functional NK activity and that differing autologous mechanisms might be reponsible for NK generation." @default.
- W2024192457 created "2016-06-24" @default.
- W2024192457 creator A5019065649 @default.
- W2024192457 creator A5044673250 @default.
- W2024192457 creator A5053977183 @default.
- W2024192457 date "1982-01-01" @default.
- W2024192457 modified "2023-09-25" @default.
- W2024192457 title "Autologous mechanisms generating natural killer activity within human peripheral lymphocytes depleted of NK target-binding cells" @default.
- W2024192457 cites W1493657798 @default.
- W2024192457 cites W1550310038 @default.
- W2024192457 cites W1562945187 @default.
- W2024192457 cites W1591495472 @default.
- W2024192457 cites W1596949665 @default.
- W2024192457 cites W1606983135 @default.
- W2024192457 cites W1925958741 @default.
- W2024192457 cites W2013482261 @default.
- W2024192457 cites W2038444011 @default.
- W2024192457 cites W2048889372 @default.
- W2024192457 cites W2091519877 @default.
- W2024192457 cites W2106560944 @default.
- W2024192457 cites W2111241013 @default.
- W2024192457 cites W2118552033 @default.
- W2024192457 cites W2143143209 @default.
- W2024192457 cites W2992693023 @default.
- W2024192457 cites W2065620250 @default.
- W2024192457 doi "https://doi.org/10.1016/0008-8749(82)90184-8" @default.
- W2024192457 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6175429" @default.
- W2024192457 hasPublicationYear "1982" @default.
- W2024192457 type Work @default.
- W2024192457 sameAs 2024192457 @default.
- W2024192457 citedByCount "4" @default.
- W2024192457 crossrefType "journal-article" @default.
- W2024192457 hasAuthorship W2024192457A5019065649 @default.
- W2024192457 hasAuthorship W2024192457A5044673250 @default.
- W2024192457 hasAuthorship W2024192457A5053977183 @default.
- W2024192457 hasConcept C109316439 @default.
- W2024192457 hasConcept C129374314 @default.
- W2024192457 hasConcept C149532602 @default.
- W2024192457 hasConcept C153911025 @default.
- W2024192457 hasConcept C154317977 @default.
- W2024192457 hasConcept C202751555 @default.
- W2024192457 hasConcept C203014093 @default.
- W2024192457 hasConcept C2776090121 @default.
- W2024192457 hasConcept C2778102761 @default.
- W2024192457 hasConcept C28651165 @default.
- W2024192457 hasConcept C3017910909 @default.
- W2024192457 hasConcept C55493867 @default.
- W2024192457 hasConcept C73588182 @default.
- W2024192457 hasConcept C86803240 @default.
- W2024192457 hasConcept C8891405 @default.
- W2024192457 hasConceptScore W2024192457C109316439 @default.
- W2024192457 hasConceptScore W2024192457C129374314 @default.
- W2024192457 hasConceptScore W2024192457C149532602 @default.
- W2024192457 hasConceptScore W2024192457C153911025 @default.
- W2024192457 hasConceptScore W2024192457C154317977 @default.
- W2024192457 hasConceptScore W2024192457C202751555 @default.
- W2024192457 hasConceptScore W2024192457C203014093 @default.
- W2024192457 hasConceptScore W2024192457C2776090121 @default.
- W2024192457 hasConceptScore W2024192457C2778102761 @default.
- W2024192457 hasConceptScore W2024192457C28651165 @default.
- W2024192457 hasConceptScore W2024192457C3017910909 @default.
- W2024192457 hasConceptScore W2024192457C55493867 @default.
- W2024192457 hasConceptScore W2024192457C73588182 @default.
- W2024192457 hasConceptScore W2024192457C86803240 @default.
- W2024192457 hasConceptScore W2024192457C8891405 @default.
- W2024192457 hasLocation W20241924571 @default.
- W2024192457 hasLocation W20241924572 @default.
- W2024192457 hasOpenAccess W2024192457 @default.
- W2024192457 hasPrimaryLocation W20241924571 @default.
- W2024192457 hasRelatedWork W2063373960 @default.
- W2024192457 hasRelatedWork W2328420645 @default.
- W2024192457 hasRelatedWork W2390253459 @default.
- W2024192457 hasRelatedWork W2398307016 @default.
- W2024192457 hasRelatedWork W2416707802 @default.
- W2024192457 hasRelatedWork W2606500760 @default.
- W2024192457 hasRelatedWork W2895407716 @default.
- W2024192457 hasRelatedWork W3036348985 @default.
- W2024192457 hasRelatedWork W3136889485 @default.
- W2024192457 hasRelatedWork W8280425 @default.
- W2024192457 isParatext "false" @default.
- W2024192457 isRetracted "false" @default.
- W2024192457 magId "2024192457" @default.
- W2024192457 workType "article" @default.