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- W2024192600 endingPage "233" @default.
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- W2024192600 abstract "Abstract Block copolymers were prepared via RAFT polymerization with P(PEGMEMA) as the hydrophilic block to form micelles for the controlled delivery of ABZ. The group contribution method was used to estimate the partial solubility parameters for ABZ and various polymers as potential core‐forming block to achieve optimum compatibility. Different ratios between MMA and LMA, a non‐compatible monomer, were prepared. Cytotoxicity tests revealed a high toxicity of the ABZ‐loaded micelle resulting in 80% cell deaths at a micelle concentration of 10 µg · mL −1 . Cellular uptake of micelles has been studied using fluorescently labeled micelles, showing that a large fraction of micelles is readily taken up by OVCAR‐3 cells. RGD‐conjugated micelles were prepared and showed an increased cellular uptake. magnified image" @default.
- W2024192600 created "2016-06-24" @default.
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- W2024192600 date "2010-11-15" @default.
- W2024192600 modified "2023-10-11" @default.
- W2024192600 title "An Optimized RGD-Decorated Micellar Drug Delivery System for Albendazole for the Treatment of Ovarian Cancer: From RAFT Polymer Synthesis to Cellular Uptake" @default.
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- W2024192600 doi "https://doi.org/10.1002/mabi.201000293" @default.
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