FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024199089> ?p ?o ?g. }

• W2024199089 endingPage "e26012" @default.
• W2024199089 startingPage "e26012" @default.
• W2024199089 abstract "Curcumin has many pharmaceutical applications, many of which arise from its potent antioxidant properties. The present research examined the antioxidant activities of curcumin in polar solvents by a comparative study using ESR, reduction of ferric iron in aqueous medium and intracellular ROS/toxicity assays. ESR data indicated that the steric hindrance among adjacent big size groups within a galvinoxyl molecule limited the curcumin to scavenge galvinoxyl radicals effectively, while curcumin showed a powerful capacity for scavenging intracellular smaller oxidative molecules such as H2O2, HO•, ROO•. Cell viability and ROS assays demonstrated that curcumin was able to penetrate into the polar medium inside the cells and to protect them against the highly toxic and lethal effects of cumene hydroperoxide. Curcumin also showed good electron-transfer capability, with greater activity than trolox in aqueous solution. Curcumin can readily transfer electron or easily donate H-atom from two phenolic sites to scavenge free radicals. The excellent electron transfer capability of curcumin is because of its unique structure and different functional groups, including a β-diketone and several π electrons that have the capacity to conjugate between two phenyl rings. Therfore, since curcumin is inherently a lipophilic compound, because of its superb intracellular ROS scavenging activity, it can be used as an effective antioxidant for ROS protection within the polar cytoplasm." @default.
• W2024199089 created "2016-06-24" @default.
• W2024199089 creator A5004697854 @default.
• W2024199089 creator A5027517298 @default.
• W2024199089 date "2011-10-10" @default.
• W2024199089 modified "2023-10-11" @default.
• W2024199089 title "Intracellular ROS Protection Efficiency and Free Radical-Scavenging Activity of Curcumin" @default.
• W2024199089 cites W1566271574 @default.
• W2024199089 cites W1590601943 @default.
• W2024199089 cites W1648278304 @default.
• W2024199089 cites W1768446746 @default.
• W2024199089 cites W1964012968 @default.
• W2024199089 cites W1969253538 @default.
• W2024199089 cites W1970411347 @default.
• W2024199089 cites W1971763901 @default.
• W2024199089 cites W1976777914 @default.
• W2024199089 cites W1986384924 @default.
• W2024199089 cites W1991963027 @default.
• W2024199089 cites W1995043836 @default.
• W2024199089 cites W2016795949 @default.
• W2024199089 cites W2017851212 @default.
• W2024199089 cites W2020526702 @default.
• W2024199089 cites W2021995332 @default.
• W2024199089 cites W2023897968 @default.
• W2024199089 cites W2025837299 @default.
• W2024199089 cites W2038526929 @default.
• W2024199089 cites W2041888873 @default.
• W2024199089 cites W2048695741 @default.
• W2024199089 cites W2057810394 @default.
• W2024199089 cites W2067574216 @default.
• W2024199089 cites W2079566113 @default.
• W2024199089 cites W2082222124 @default.
• W2024199089 cites W2084203246 @default.
• W2024199089 cites W2114467922 @default.
• W2024199089 cites W2115841218 @default.
• W2024199089 cites W2116060738 @default.
• W2024199089 cites W2141515673 @default.
• W2024199089 cites W2157067671 @default.
• W2024199089 cites W2160800370 @default.
• W2024199089 cites W2165201727 @default.
• W2024199089 cites W2336732799 @default.
• W2024199089 cites W34120688 @default.
• W2024199089 cites W39977911 @default.
• W2024199089 doi "https://doi.org/10.1371/journal.pone.0026012" @default.
• W2024199089 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3189944" @default.
• W2024199089 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22016801" @default.
• W2024199089 hasPublicationYear "2011" @default.
• W2024199089 type Work @default.
• W2024199089 sameAs 2024199089 @default.
• W2024199089 citedByCount "254" @default.
• W2024199089 countsByYear W20241990892012 @default.
• W2024199089 countsByYear W20241990892013 @default.
• W2024199089 countsByYear W20241990892014 @default.
• W2024199089 countsByYear W20241990892015 @default.
• W2024199089 countsByYear W20241990892016 @default.
• W2024199089 countsByYear W20241990892017 @default.
• W2024199089 countsByYear W20241990892018 @default.
• W2024199089 countsByYear W20241990892019 @default.
• W2024199089 countsByYear W20241990892020 @default.
• W2024199089 countsByYear W20241990892021 @default.
• W2024199089 countsByYear W20241990892022 @default.
• W2024199089 countsByYear W20241990892023 @default.
• W2024199089 crossrefType "journal-article" @default.
• W2024199089 hasAuthorship W2024199089A5004697854 @default.
• W2024199089 hasAuthorship W2024199089A5027517298 @default.
• W2024199089 hasBestOaLocation W20241990891 @default.
• W2024199089 hasConcept C12554922 @default.
• W2024199089 hasConcept C139066938 @default.
• W2024199089 hasConcept C178790620 @default.
• W2024199089 hasConcept C185592680 @default.
• W2024199089 hasConcept C2776231299 @default.
• W2024199089 hasConcept C2778004101 @default.
• W2024199089 hasConcept C2778250585 @default.
• W2024199089 hasConcept C2780534640 @default.
• W2024199089 hasConcept C2781401929 @default.
• W2024199089 hasConcept C55493867 @default.
• W2024199089 hasConcept C79879829 @default.
• W2024199089 hasConcept C86803240 @default.
• W2024199089 hasConceptScore W2024199089C12554922 @default.
• W2024199089 hasConceptScore W2024199089C139066938 @default.
• W2024199089 hasConceptScore W2024199089C178790620 @default.
• W2024199089 hasConceptScore W2024199089C185592680 @default.
• W2024199089 hasConceptScore W2024199089C2776231299 @default.
• W2024199089 hasConceptScore W2024199089C2778004101 @default.
• W2024199089 hasConceptScore W2024199089C2778250585 @default.
• W2024199089 hasConceptScore W2024199089C2780534640 @default.
• W2024199089 hasConceptScore W2024199089C2781401929 @default.
• W2024199089 hasConceptScore W2024199089C55493867 @default.
• W2024199089 hasConceptScore W2024199089C79879829 @default.
• W2024199089 hasConceptScore W2024199089C86803240 @default.
• W2024199089 hasIssue "10" @default.
• W2024199089 hasLocation W20241990891 @default.
• W2024199089 hasLocation W20241990892 @default.
• W2024199089 hasLocation W20241990893 @default.
• W2024199089 hasLocation W20241990894 @default.
• W2024199089 hasLocation W20241990895 @default.
• W2024199089 hasOpenAccess W2024199089 @default.
• W2024199089 hasPrimaryLocation W20241990891 @default.

• next