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- W2024208082 abstract "Synthesis of enantiomerically pure (S)-(−)-propranolol, the most active optical isomer of the widely used β-Sympatholyticum, was achieved in high optical yield starting from sorbitol, an inexpensive and easily accessible carbohydrate. Via regioselective protection and coupling of α-naphthol, the key intermediate 5 was obtained. Deprotection of the intermediate acetals and successive oxidative degradation followed by some simple conversion steps lead to the formation of (S)-(−)-propranolol with high optically purity." @default.
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- W2024208082 title "Synthesis of enantiomerically pure (S)-(−)-propranolol from sorbitol" @default.
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