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• W2024224215 abstract "A new pyranonaphthoquinone antibiotic, griseusin D (1) was isolated from the cultural fluid of the alkaphilic Nocardiopsis sp. The structure was determined as 5'-one-4-hydroxy-12-methoxygriseusin by spectroscopic methods, comparison with reported data and single-crystal X-ray analysis. 1 displayed strong cytotoxicity against human leukemia cells (HL60) and modest cytotoxicity against human lung adenocarcinoma cell lines (AGZY) with IC(50) values of 0.23 and 19.6 microg/ml, respectively. It also exhibited weak antifungal activity against Alternaria alternate with MIC of 140 microg/ml." @default.
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• W2024224215 date "2007-12-01" @default.
• W2024224215 modified "2023-10-01" @default.
• W2024224215 title "Griseusin D, a New Pyranonaphthoquinone Derivative from a Alkaphilic Nocardiopsis sp." @default.
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• W2024224215 doi "https://doi.org/10.1038/ja.2007.100" @default.
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