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- W2024227714 abstract "The yolk protein 1 gene (yp1) of Drosophila melanogaster is expressed only in the ovarian follicle cells and the fat bodies of adult females. We have previously shown that a different cis-acting DNA region is required for each of these tissue specificities. In this paper we use germ line transformation to localize and characterized one of these tissue-specific regulatory regions. We demonstrate that a 125 bp segment of DNA located 196 bp upstream of the yp1 cap site is sufficient to determine the sex-, stage-, and fat body-specific expression of the yp1 gene. We also find that this region can confer yp1-specific expression on a heterologous Drosophila promoter. This specificity is retained when the region is in different orientations and at different distances from the heterologous promoter. Thus a small regulatory region acts in vivo as a positive enhancer to determine the fat body expression pattern of yp1." @default.
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- W2024227714 date "1986-06-01" @default.
- W2024227714 modified "2023-10-17" @default.
- W2024227714 title "A tissue-specific transcription enhancer from the Drosophila yolk protein 1 gene" @default.
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- W2024227714 doi "https://doi.org/10.1016/0092-8674(86)90560-x" @default.
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