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- W2024240410 abstract "Our knowledge of the genetic regulation of enzyme synthesis is largely derived from experiments with bacteria and viruses. It is of obvious interest to inquire whether the genetic regulation of enzyme induction and repression in higher organisms involves any novel features. A possible point of difference is the presence of a nuclear membrane in eukaryotes as distinct from prokaryotes (Ris and Chandler, 1963). It is generally believed that the repressive product of the regulator gene acts on the chromosome. If the nuclear membrane were impermeable to the repressor in either direction, the domain of action of each regulator gene would be limited to a single nucleus. It has been suggested that this is indeed so, and certain mutations which complement each other in diploids but not in heterokaryons involve the regulatory genes (Pontecorvo, 1963; Roberts, 1964). In order to test this possibility we have undertaken a study of a regulated..." @default.
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- W2024240410 date "1966-01-01" @default.
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- W2024240410 title "Genetic Regulation of Aryl Sulphatases in Aspergillus nidulans" @default.
- W2024240410 doi "https://doi.org/10.1101/sqb.1966.031.01.049" @default.
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