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• W2024248093 abstract "Extracellular Toxoplasma parasites are sensitive to pyrrolidine dithiocarbamate (PDTC) at low micromolar concentrations. Loss of parasite viability following PDTC treatment is shown to be mediated by oxidation, which is reminiscent of PDTC killing in mammalian cells. Intracellular parasites, by contrast, are resistant to PDTC killing, although treatment does cause reversible growth arrest. In addition to the possible implications relative to the biology of the parasite, these observations suggest that PDTC could be of use in eliminating undesired extracellular parasites during assays and selections in vitro." @default.
• W2024248093 created "2016-06-24" @default.
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• W2024248093 date "2001-08-01" @default.
• W2024248093 modified "2023-09-23" @default.
• W2024248093 title "Toxoplasma gondii: Selective Killing of Extracellular Parasites by Oxidation Using Pyrrolidine Dithiocarbamate" @default.
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• W2024248093 doi "https://doi.org/10.1006/expr.2001.4636" @default.
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