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- W2024253963 abstract "PCBs are a persistent environmental problem due to their high stability and lipophilicity. The non-ortho- and the mono-ortho-substituted PCBs (dioxin-like-PCBs) share a common and well-described toxicity mechanism in vertebrates, initially involving binding to cytosolic AhRs. Invertebrate AhRs, however, show a lack of dioxin binding, and little information is available regarding the mechanism of toxicity of dl-PCBs in invertebrates. In this study, a proteomic approach was applied to analyse the variations in the pattern of the gill proteome of the freshwater mussel Dreissena polymorpha. Mussels were exposed to a mixture of dl-PCBs, and to perform a more in-depth evaluation, we chose to investigate the role of gender in the proteome response by analysing male and female mussels separately. The results revealed significant modulation of the gill tissue proteome: glycolysis and Ca2 + homeostasis appear to be the main pathways targeted by dl-PCBs. In light of the differences between the male and female gill proteome profiles following exposure to dl-PCBs, further in-depth investigations of the role of gender in the protein expression profiles of a selected biological model are required." @default.
- W2024253963 created "2016-06-24" @default.
- W2024253963 creator A5054887054 @default.
- W2024253963 creator A5071641057 @default.
- W2024253963 date "2014-03-01" @default.
- W2024253963 modified "2023-09-26" @default.
- W2024253963 title "Analysis of the Dreissena polymorpha gill proteome following exposure to dioxin-like PCBs: Mechanism of action and the role of gender" @default.
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- W2024253963 cites W1967955590 @default.
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- W2024253963 cites W1968958197 @default.
- W2024253963 cites W1969136753 @default.
- W2024253963 cites W1972728574 @default.
- W2024253963 cites W1976229657 @default.
- W2024253963 cites W1977414534 @default.
- W2024253963 cites W1978237064 @default.
- W2024253963 cites W1980022967 @default.
- W2024253963 cites W1980964194 @default.
- W2024253963 cites W1982010370 @default.
- W2024253963 cites W1986043450 @default.
- W2024253963 cites W1986863125 @default.
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- W2024253963 cites W1989099516 @default.
- W2024253963 cites W1990433000 @default.
- W2024253963 cites W1990726783 @default.
- W2024253963 cites W1995702065 @default.
- W2024253963 cites W1996253097 @default.
- W2024253963 cites W1996457746 @default.
- W2024253963 cites W2006055376 @default.
- W2024253963 cites W2010422847 @default.
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- W2024253963 cites W2011582760 @default.
- W2024253963 cites W2013599464 @default.
- W2024253963 cites W2015213995 @default.
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- W2024253963 cites W2016535776 @default.
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- W2024253963 cites W2040204935 @default.
- W2024253963 cites W2042185075 @default.
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- W2024253963 cites W2044511746 @default.
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- W2024253963 cites W2046184567 @default.
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- W2024253963 cites W2074644349 @default.
- W2024253963 cites W2075340093 @default.
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- W2024253963 cites W2083563797 @default.
- W2024253963 cites W2087054927 @default.
- W2024253963 cites W2093861673 @default.
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- W2024253963 cites W3163493610 @default.
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- W2024253963 doi "https://doi.org/10.1016/j.cbd.2013.08.005" @default.
- W2024253963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24365568" @default.
- W2024253963 hasPublicationYear "2014" @default.
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