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- W2024258105 abstract "A highly efficient route for the conversion of the antimalarial drug artemisinin to a novel hydroxy-functionalized tricyclic 1,2,4-trioxane 6 is reported. Neither the trioxane 6 nor its derivatives 14−16, all of which lack the hydrolytically unstable acetal−lactone linkage, show antimalarial activity comparable with that of artemisinin." @default.
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- W2024258105 date "2007-09-18" @default.
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- W2024258105 title "Conversion of Antimalarial Drug Artemisinin to a New Series of Tricyclic 1,2,4-Trioxanes<sup>1</sup>" @default.
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- W2024258105 doi "https://doi.org/10.1021/ol701887x" @default.
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