FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024259942> ?p ?o ?g. }

• W2024259942 endingPage "2616" @default.
• W2024259942 startingPage "2608" @default.
• W2024259942 abstract "ABSTRACT Isavuconazole is a new broad-spectrum triazole with a favorable pharmacokinetic and safety profile. We report the MIC distributions for isavuconazole and 111 isolates of Candida (42 Candida albicans , 25 Candida glabrata , 22 Candida parapsilosis , 14 Candida tropicalis , and 8 Candida krusei isolates), as determined by Clinical and Laboratory Standards Institute (CLSI) and European Committee on Antimicrobial Susceptibility Testing (EUCAST) broth microdilution (BMD) methods. Also, the relative activities of isavuconazole, itraconazole, fluconazole, posaconazole, voriconazole, and the three echinocandins were assessed against a recent (2011) global collection of 1,358 isolates of Candida spp., 101 of Aspergillus spp., 54 of non- Candida yeasts, and 21 of non- Aspergillus molds using CLSI BMD methods. The overall essential agreement (EA) (±2 log 2 dilutions) between the CLSI and EUCAST methods was 99.1% (EA at ±1 log 2 dilution, 90.1% [range, 80.0 to 100.0%]). The activities of isavuconazole against the larger collection of Candida spp. and Aspergillus spp. were comparable to those of posaconazole and voriconazole; the MIC 90 values for isavuconazole, posaconazole, and voriconazole against Candida spp. were 0.5, 1, and 0.25 μg/ml and against Aspergillus spp. were 2, 1, and 1 μg/ml, respectively. Isavuconazole showed good activities against Cryptococcus neoformans (MIC 90 , 0.12 μg/ml) and other non- Candida yeasts (MIC 90 , 1 μg/ml) but was less potent against non- Aspergillus molds (MIC 90 , >8 μg/ml). Isavuconazole MIC values for three mucormycete isolates were 4, 1, and 2 μg/ml, whereas all three were inhibited by 1 μg/ml posaconazole. Isavuconazole demonstrates broad-spectrum activity against this global collection of opportunistic fungi, and the CLSI and EUCAST methods can be used to test this agent against Candida , with highly comparable results." @default.
• W2024259942 created "2016-06-24" @default.
• W2024259942 creator A5026620873 @default.
• W2024259942 creator A5028081249 @default.
• W2024259942 creator A5028739024 @default.
• W2024259942 creator A5050247239 @default.
• W2024259942 creator A5073303672 @default.
• W2024259942 date "2013-08-01" @default.
• W2024259942 modified "2023-10-18" @default.
• W2024259942 title "<i>In Vitro</i> Activities of Isavuconazole and Comparator Antifungal Agents Tested against a Global Collection of Opportunistic Yeasts and Molds" @default.
• W2024259942 cites W12653918 @default.
• W2024259942 cites W1972692992 @default.
• W2024259942 cites W1973187167 @default.
• W2024259942 cites W1981025594 @default.
• W2024259942 cites W1998062381 @default.
• W2024259942 cites W2002603789 @default.
• W2024259942 cites W2018296505 @default.
• W2024259942 cites W2032893561 @default.
• W2024259942 cites W2043176567 @default.
• W2024259942 cites W2053244845 @default.
• W2024259942 cites W2058571383 @default.
• W2024259942 cites W2062983075 @default.
• W2024259942 cites W2067050070 @default.
• W2024259942 cites W2069678662 @default.
• W2024259942 cites W2075052146 @default.
• W2024259942 cites W2084643045 @default.
• W2024259942 cites W2099898423 @default.
• W2024259942 cites W2102596464 @default.
• W2024259942 cites W2107719786 @default.
• W2024259942 cites W2110459852 @default.
• W2024259942 cites W2114606058 @default.
• W2024259942 cites W2120299440 @default.
• W2024259942 cites W2123134253 @default.
• W2024259942 cites W2128463316 @default.
• W2024259942 cites W2137117173 @default.
• W2024259942 cites W2138137359 @default.
• W2024259942 cites W2138945621 @default.
• W2024259942 cites W2140968247 @default.
• W2024259942 cites W2145095507 @default.
• W2024259942 cites W2145284856 @default.
• W2024259942 cites W2148849112 @default.
• W2024259942 cites W2150428940 @default.
• W2024259942 cites W2154336328 @default.
• W2024259942 cites W2169748580 @default.
• W2024259942 cites W2170595857 @default.
• W2024259942 doi "https://doi.org/10.1128/jcm.00863-13" @default.
• W2024259942 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3719620" @default.
• W2024259942 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23740727" @default.
• W2024259942 hasPublicationYear "2013" @default.
• W2024259942 type Work @default.
• W2024259942 sameAs 2024259942 @default.
• W2024259942 citedByCount "76" @default.
• W2024259942 countsByYear W20242599422013 @default.
• W2024259942 countsByYear W20242599422014 @default.
• W2024259942 countsByYear W20242599422015 @default.
• W2024259942 countsByYear W20242599422016 @default.
• W2024259942 countsByYear W20242599422017 @default.
• W2024259942 countsByYear W20242599422018 @default.
• W2024259942 countsByYear W20242599422019 @default.
• W2024259942 countsByYear W20242599422020 @default.
• W2024259942 countsByYear W20242599422021 @default.
• W2024259942 countsByYear W20242599422022 @default.
• W2024259942 countsByYear W20242599422023 @default.
• W2024259942 crossrefType "journal-article" @default.
• W2024259942 hasAuthorship W2024259942A5026620873 @default.
• W2024259942 hasAuthorship W2024259942A5028081249 @default.
• W2024259942 hasAuthorship W2024259942A5028739024 @default.
• W2024259942 hasAuthorship W2024259942A5050247239 @default.
• W2024259942 hasAuthorship W2024259942A5073303672 @default.
• W2024259942 hasBestOaLocation W20242599421 @default.
• W2024259942 hasConcept C176947019 @default.
• W2024259942 hasConcept C2775835631 @default.
• W2024259942 hasConcept C2777071850 @default.
• W2024259942 hasConcept C2778566413 @default.
• W2024259942 hasConcept C2779175654 @default.
• W2024259942 hasConcept C2779443200 @default.
• W2024259942 hasConcept C2779548794 @default.
• W2024259942 hasConcept C2780651595 @default.
• W2024259942 hasConcept C2780670043 @default.
• W2024259942 hasConcept C2780690907 @default.
• W2024259942 hasConcept C2780917455 @default.
• W2024259942 hasConcept C2780950330 @default.
• W2024259942 hasConcept C2781425774 @default.
• W2024259942 hasConcept C4937899 @default.
• W2024259942 hasConcept C86803240 @default.
• W2024259942 hasConcept C89423630 @default.
• W2024259942 hasConceptScore W2024259942C176947019 @default.
• W2024259942 hasConceptScore W2024259942C2775835631 @default.
• W2024259942 hasConceptScore W2024259942C2777071850 @default.
• W2024259942 hasConceptScore W2024259942C2778566413 @default.
• W2024259942 hasConceptScore W2024259942C2779175654 @default.
• W2024259942 hasConceptScore W2024259942C2779443200 @default.
• W2024259942 hasConceptScore W2024259942C2779548794 @default.
• W2024259942 hasConceptScore W2024259942C2780651595 @default.
• W2024259942 hasConceptScore W2024259942C2780670043 @default.
• W2024259942 hasConceptScore W2024259942C2780690907 @default.
• W2024259942 hasConceptScore W2024259942C2780917455 @default.
• W2024259942 hasConceptScore W2024259942C2780950330 @default.

• next