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• W2024261607 abstract "Four chemically processed grafts implanted as arterial substitutes in dogs were evaluated as blood conduits in terms of patency rates, healing characteristics and biostability. Omniflow®, Biopolymeric®, Dardik-Biograft® of the second generation and BIMA® grafts were implanted as infrarenal aortic substitutes for 4, 24 and 48 h (short-term), 1, 2 and 4 wk (medium-term), 3 and 6 month (long-term), each type of graft being implanted for a complete series. The explanted grafts were evaluated macroscopically and processed for light and scanning electron microscopy. One Omniflow® graft was occluded at 6 month and two Dardik-Biografts® were thrombosed, one at 24 h and one at 1month. All explanted grafts in the Biopolymeric® series and in the BIMA® were patent at the animals' death. Histological studies revealed frequent subintimal fibrosis in the Biopolymeric® and Omniflow grafts. A peripheral inflammatory reaction was present in most grafts explanted. Scanning electron microscopy showed an aggravation of flow surface irregularities, after implantation of Omniflow®, Biopolymeric® and Dardik-Biograft®, compared to virgin prostheses. These grafts presented an internal capsulae on the graft flow surface along the anastomoses. The capsulae slightly extended towards the centre of the graft after long-term implantation, (6 month) and corresponded to the pannus. Endothelial-like cells covered this pannus. The BIMA® graft performed the most satisfactorily and retained its blood compatibility best, that is, the luminal surface was smooth with only minor thrombotic deposits and a thin pannus along the anastomotic lines." @default.
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• W2024261607 date "1989-08-01" @default.
• W2024261607 modified "2023-09-27" @default.
• W2024261607 title "In vivo evaluation of four chemically processed biological grafts implanted as infrarenal arterial substitutes in dogs" @default.
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• W2024261607 doi "https://doi.org/10.1016/0142-9612(89)90128-2" @default.
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