FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024263951> ?p ?o ?g. }

• W2024263951 endingPage "3613" @default.
• W2024263951 startingPage "3605" @default.
• W2024263951 abstract "The C-terminus of the intracellular retinal rod outer segment disk protein peripherin-2 binds to membranes, adopts a helical conformation, and promotes membrane fusion, which suggests an analogy to the structure and function of viral envelope fusion proteins. Nuclear magnetic resonance (NMR) data and fluorescence data show that a 63-residue polypeptide comprising the C-terminus of bovine peripherin-2 (R284-G346) binds to the membrane mimetic, dodecylphosphocholine micelles. High-resolution NMR studies reveal that although this C-terminal fragment is unstructured in solution, the same fragment adopts helical structure when bound to the micelles. The C-terminus may be a member of the class of intrinsically unstructured protein domains. Using methods developed for the G-protein coupled receptor rhodopsin, a model for the structure of the transmembrane domain of peripherin-2 was constructed. Previously published data showed that both peripherin-2 and viral fusion proteins are transmembrane proteins that promote membrane fusion and have a fusion peptide sequence within the protein that independently promotes membrane fusion. Furthermore, the fusion-active sequence of peripherin-2 exhibits a sequence motif that matches the viral fusion peptide of influenza hemagglutinin (HA). These observations collectively suggest that the mechanism of intracellular membrane fusion induced by peripherin-2 and the mechanism of enveloped viral fusion may have features in common." @default.
• W2024263951 created "2016-06-24" @default.
• W2024263951 creator A5001041858 @default.
• W2024263951 creator A5008925743 @default.
• W2024263951 creator A5039025646 @default.
• W2024263951 creator A5049880042 @default.
• W2024263951 creator A5090087970 @default.
• W2024263951 date "2007-02-27" @default.
• W2024263951 modified "2023-10-18" @default.
• W2024263951 title "Peripherin-2: An Intracellular Analogy to Viral Fusion Proteins" @default.
• W2024263951 cites W1445935732 @default.
• W2024263951 cites W1539947129 @default.
• W2024263951 cites W1544329852 @default.
• W2024263951 cites W162507564 @default.
• W2024263951 cites W1677949299 @default.
• W2024263951 cites W1971976535 @default.
• W2024263951 cites W1975304761 @default.
• W2024263951 cites W1981862901 @default.
• W2024263951 cites W2006192061 @default.
• W2024263951 cites W2030083791 @default.
• W2024263951 cites W2041391074 @default.
• W2024263951 cites W2063636670 @default.
• W2024263951 cites W2071341991 @default.
• W2024263951 cites W2075967815 @default.
• W2024263951 cites W2169821755 @default.
• W2024263951 doi "https://doi.org/10.1021/bi061820c" @default.
• W2024263951 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17323921" @default.
• W2024263951 hasPublicationYear "2007" @default.
• W2024263951 type Work @default.
• W2024263951 sameAs 2024263951 @default.
• W2024263951 citedByCount "17" @default.
• W2024263951 countsByYear W20242639512012 @default.
• W2024263951 countsByYear W20242639512013 @default.
• W2024263951 countsByYear W20242639512015 @default.
• W2024263951 countsByYear W20242639512016 @default.
• W2024263951 countsByYear W20242639512017 @default.
• W2024263951 countsByYear W20242639512018 @default.
• W2024263951 countsByYear W20242639512019 @default.
• W2024263951 countsByYear W20242639512021 @default.
• W2024263951 countsByYear W20242639512023 @default.
• W2024263951 crossrefType "journal-article" @default.
• W2024263951 hasAuthorship W2024263951A5001041858 @default.
• W2024263951 hasAuthorship W2024263951A5008925743 @default.
• W2024263951 hasAuthorship W2024263951A5039025646 @default.
• W2024263951 hasAuthorship W2024263951A5049880042 @default.
• W2024263951 hasAuthorship W2024263951A5090087970 @default.
• W2024263951 hasConcept C103038307 @default.
• W2024263951 hasConcept C104317684 @default.
• W2024263951 hasConcept C108625454 @default.
• W2024263951 hasConcept C118892022 @default.
• W2024263951 hasConcept C123894998 @default.
• W2024263951 hasConcept C12554922 @default.
• W2024263951 hasConcept C144647389 @default.
• W2024263951 hasConcept C170493617 @default.
• W2024263951 hasConcept C173414695 @default.
• W2024263951 hasConcept C185592680 @default.
• W2024263951 hasConcept C202033177 @default.
• W2024263951 hasConcept C24530287 @default.
• W2024263951 hasConcept C2780827179 @default.
• W2024263951 hasConcept C28521208 @default.
• W2024263951 hasConcept C2909404852 @default.
• W2024263951 hasConcept C40767141 @default.
• W2024263951 hasConcept C41625074 @default.
• W2024263951 hasConcept C55493867 @default.
• W2024263951 hasConcept C86803240 @default.
• W2024263951 hasConcept C95444343 @default.
• W2024263951 hasConcept C97380033 @default.
• W2024263951 hasConceptScore W2024263951C103038307 @default.
• W2024263951 hasConceptScore W2024263951C104317684 @default.
• W2024263951 hasConceptScore W2024263951C108625454 @default.
• W2024263951 hasConceptScore W2024263951C118892022 @default.
• W2024263951 hasConceptScore W2024263951C123894998 @default.
• W2024263951 hasConceptScore W2024263951C12554922 @default.
• W2024263951 hasConceptScore W2024263951C144647389 @default.
• W2024263951 hasConceptScore W2024263951C170493617 @default.
• W2024263951 hasConceptScore W2024263951C173414695 @default.
• W2024263951 hasConceptScore W2024263951C185592680 @default.
• W2024263951 hasConceptScore W2024263951C202033177 @default.
• W2024263951 hasConceptScore W2024263951C24530287 @default.
• W2024263951 hasConceptScore W2024263951C2780827179 @default.
• W2024263951 hasConceptScore W2024263951C28521208 @default.
• W2024263951 hasConceptScore W2024263951C2909404852 @default.
• W2024263951 hasConceptScore W2024263951C40767141 @default.
• W2024263951 hasConceptScore W2024263951C41625074 @default.
• W2024263951 hasConceptScore W2024263951C55493867 @default.
• W2024263951 hasConceptScore W2024263951C86803240 @default.
• W2024263951 hasConceptScore W2024263951C95444343 @default.
• W2024263951 hasConceptScore W2024263951C97380033 @default.
• W2024263951 hasIssue "12" @default.
• W2024263951 hasLocation W20242639511 @default.
• W2024263951 hasLocation W20242639512 @default.
• W2024263951 hasOpenAccess W2024263951 @default.
• W2024263951 hasPrimaryLocation W20242639511 @default.
• W2024263951 hasRelatedWork W120961283 @default.
• W2024263951 hasRelatedWork W2024263951 @default.
• W2024263951 hasRelatedWork W2092236780 @default.
• W2024263951 hasRelatedWork W2148460306 @default.
• W2024263951 hasRelatedWork W2163451196 @default.

• next