FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024264511> ?p ?o ?g. }

• W2024264511 endingPage "137" @default.
• W2024264511 startingPage "119" @default.
• W2024264511 abstract "Before the initial introduction of generalized anxiety disorder (GAD) in the DSM-III, patients with severe and chronic anxiety were given the diagnosis of anxiety neurosis, a term introduced by Freud more than 100 years ago. In the DSM-III, the subcategory of “anxiety neurosis” became “anxiety states” that included panic disorder, GAD, and obsessive-compulsive disorder; however, DSM-III–defined GAD represented a residual diagnosis that could not be assigned if patients met criteria for another mental disorder. That residual status of GAD was dropped in the DSM-III-R, allowing an independent diagnosis of GAD in addition to other mental disorders. The American Psychiatric Association also revised the diagnostic criteria for GAD, requiring the presence of unrealistic, excessive anxiety and worry for at least 6 months as manifested by at least 6 symptoms from a list of 18 somatic symptoms, which formed three clusters of motor tension, autonomic hyperactivity, vigilance, and scanning. In 1994, the DSM-IV Anxiety Task Force made further revisions to those earlier DSM-III-R diagnostic criteria for GAD. Some of the more substantial revisions made in the DSM-IV included increased emphasis on uncontrollable worry and less emphasis on autonomic symptoms, requiring only six physical symptom criteria (e.g., restlessness or feeling “keyed up” or “on edge,” being easily fatigued, difficulty concentrating or mind “going blank,” irritability, muscle tension, and sleep disturbance). This reduction was accomplished by empiric studies of GAD patients that resulted in the elimination of symptoms constituting the autonomic hyperactivity cluster that were found to be only infrequently endorsed by patients with GAD.6, 42 Although, in the past, the validity of GAD as an independent diagnostic category was questioned, increasing data indicate that GAD is a common, severe, and distinct illness that leads to significant morbidity.9, 43, 51, 63, 87 Also, GAD seems to carry a significant “price tag” to the affected individual and to society.82 Unfortunately, in contrast to other anxiety disorders, relatively less attention has been devoted to the investigation of the biological correlates and, subsequently, the pharmacologic treatments for GAD. The shifting diagnostic criteria, the concerns about low diagnostic reliability in many studies, and questions regarding its validity may have contributed to the limited research of GAD. Thus, certain issues, such as comparative efficacy of pharmacotherapies in the treatment of patients with GAD, long-term treatment, and medication discontinuation, remained largely unexplored. This article reviews the available data on the pharmacologic treatment of patients with GAD, with additional emphasis on treatment of comorbid conditions, and treatment resistance." @default.
• W2024264511 created "2016-06-24" @default.
• W2024264511 creator A5090144152 @default.
• W2024264511 date "2001-03-01" @default.
• W2024264511 modified "2023-10-18" @default.
• W2024264511 title "Pharmacologic Treatment of Generalized Anxiety Disorder" @default.
• W2024264511 cites W133794067 @default.
• W2024264511 cites W1563799145 @default.
• W2024264511 cites W1640209568 @default.
• W2024264511 cites W1718879924 @default.
• W2024264511 cites W1812428887 @default.
• W2024264511 cites W1916496493 @default.
• W2024264511 cites W1967003846 @default.
• W2024264511 cites W1972153662 @default.
• W2024264511 cites W1975806198 @default.
• W2024264511 cites W1979350490 @default.
• W2024264511 cites W1981272264 @default.
• W2024264511 cites W1981315251 @default.
• W2024264511 cites W1981776119 @default.
• W2024264511 cites W1984623076 @default.
• W2024264511 cites W1990408097 @default.
• W2024264511 cites W1992176680 @default.
• W2024264511 cites W1993794887 @default.
• W2024264511 cites W1994901395 @default.
• W2024264511 cites W1995006301 @default.
• W2024264511 cites W2001750700 @default.
• W2024264511 cites W2001949258 @default.
• W2024264511 cites W2002519594 @default.
• W2024264511 cites W2007260364 @default.
• W2024264511 cites W2009032717 @default.
• W2024264511 cites W2014112569 @default.
• W2024264511 cites W2018764502 @default.
• W2024264511 cites W2027104154 @default.
• W2024264511 cites W2030139281 @default.
• W2024264511 cites W2037875799 @default.
• W2024264511 cites W2039895052 @default.
• W2024264511 cites W2040537436 @default.
• W2024264511 cites W2042605575 @default.
• W2024264511 cites W2047192206 @default.
• W2024264511 cites W2049728968 @default.
• W2024264511 cites W2059637464 @default.
• W2024264511 cites W2063980879 @default.
• W2024264511 cites W2065747869 @default.
• W2024264511 cites W2074130396 @default.
• W2024264511 cites W2078342795 @default.
• W2024264511 cites W2084331258 @default.
• W2024264511 cites W2084647052 @default.
• W2024264511 cites W2092760765 @default.
• W2024264511 cites W2102221545 @default.
• W2024264511 cites W2108460780 @default.
• W2024264511 cites W2136635083 @default.
• W2024264511 cites W2152069111 @default.
• W2024264511 cites W2159412346 @default.
• W2024264511 cites W2314952544 @default.
• W2024264511 cites W2328319678 @default.
• W2024264511 cites W2400172486 @default.
• W2024264511 cites W2404271198 @default.
• W2024264511 cites W2413307415 @default.
• W2024264511 cites W2425288672 @default.
• W2024264511 cites W2472669205 @default.
• W2024264511 cites W2765030473 @default.
• W2024264511 cites W4206621253 @default.
• W2024264511 cites W4241457988 @default.
• W2024264511 cites W4254339345 @default.
• W2024264511 cites W4299480746 @default.
• W2024264511 cites W4301751484 @default.
• W2024264511 cites W47806681 @default.
• W2024264511 cites W69979210 @default.
• W2024264511 cites W76596067 @default.
• W2024264511 doi "https://doi.org/10.1016/s0193-953x(05)70209-4" @default.
• W2024264511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11225503" @default.
• W2024264511 hasPublicationYear "2001" @default.
• W2024264511 type Work @default.
• W2024264511 sameAs 2024264511 @default.
• W2024264511 citedByCount "32" @default.
• W2024264511 countsByYear W20242645112012 @default.
• W2024264511 countsByYear W20242645112016 @default.
• W2024264511 countsByYear W20242645112020 @default.
• W2024264511 crossrefType "journal-article" @default.
• W2024264511 hasAuthorship W2024264511A5090144152 @default.
• W2024264511 hasConcept C118552586 @default.
• W2024264511 hasConcept C15744967 @default.
• W2024264511 hasConcept C2776317618 @default.
• W2024264511 hasConcept C2777529043 @default.
• W2024264511 hasConcept C2779911313 @default.
• W2024264511 hasConcept C2779978724 @default.
• W2024264511 hasConcept C2780820931 @default.
• W2024264511 hasConcept C558461103 @default.
• W2024264511 hasConcept C70410870 @default.
• W2024264511 hasConceptScore W2024264511C118552586 @default.
• W2024264511 hasConceptScore W2024264511C15744967 @default.
• W2024264511 hasConceptScore W2024264511C2776317618 @default.
• W2024264511 hasConceptScore W2024264511C2777529043 @default.
• W2024264511 hasConceptScore W2024264511C2779911313 @default.
• W2024264511 hasConceptScore W2024264511C2779978724 @default.
• W2024264511 hasConceptScore W2024264511C2780820931 @default.
• W2024264511 hasConceptScore W2024264511C558461103 @default.
• W2024264511 hasConceptScore W2024264511C70410870 @default.

• next