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- W2024264965 abstract "GacS/GacA global two-component regulatory systems are comprised of a membrane-bound environmental sensor, GacS, and a transcriptional response regulator, GacA. GacS/ GacA homologs have since been identified in some plant pathogenic bacterial. A current model proposes that GacS senses a still-unknown signal and activates, via a phosphorelay mechanism, the GacA transcription regulator, which in turn triggers the expression of target genes. Certain genes whose expression is regulated by the GacS/GacA system are regulated in parallel by the small RNA binding protein RsmA (CsrA) at a posttranscriptional level. It is suggested that the GacS/GacA system operates a switch between primary and secondary metabolism, with a major involvement of posttranscriptional control mechanisms." @default.
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- W2024264965 date "2012-05-01" @default.
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- W2024264965 title "Molecular Mechanisms of Two-Component System GacS/GacA in Plant-Pathogenic Bacteria" @default.
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- W2024264965 doi "https://doi.org/10.1109/icbeb.2012.477" @default.
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