FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024273399> ?p ?o ?g. }

• W2024273399 endingPage "6" @default.
• W2024273399 startingPage "1" @default.
• W2024273399 abstract "Background: Progressive fibrosis and cirrhosis, clinically presenting as end-stage liver disease are common outcomes in alcoholic hepatitis as well as non-alcoholic fatty liver disease(NAFLD). In these processes, a series of changes occurs in liver tissues leading to cell death, remodeling, fibrosis and regeneration. The aim of this study is to identify potential novel biomarkers for non-invasive diagnosis of cirrhosis due to alcoholic etiology or NAFLD. Methods: Serum from patients with biopsy proven end-stage liver disease of various etiologies, namely NAFLD(n=9), alcohol( n=5), and other end-stage liver diseases(n=6), who underwent liver transplant during the first six months of 2007 were utilized for retrospective analysis. Serum samples were also collected from a group of healthy volunteers (n=7). The samples were analysed using Luminex technology or ELISA for 27 biomarkers that are known to be involved in pathologic processes such as cell death, regeneration and fibrosis. Results: Of the 27 serum markers examined, 16 were elevated in the serum in all groups with end-stage liver diseases compared with the control group. They include adipokines, apoptosis and inflammatory mediators and growth factors. Interestingly, the serum of NAFLD patients showed significantly elevated HGF levels and trend towards increase in sFAS, TGF􀀁1, TNFR-1, TNFR-2 and leptin. The level of serum markers showed excellent correlation with each other indicating a complex interdependent pathogenetic mechanism. Conclusions: The data from this study indicate that a large number of serum markers are altered in end-stage liver diseases. A panel of such markers may potentially be useful in assessing advanced fibrosis and cirrhosis in patients with chronic end stage liver diseases." @default.
• W2024273399 created "2016-06-24" @default.
• W2024273399 creator A5022883772 @default.
• W2024273399 creator A5030435077 @default.
• W2024273399 creator A5033962588 @default.
• W2024273399 creator A5059680705 @default.
• W2024273399 creator A5067214484 @default.
• W2024273399 creator A5090787460 @default.
• W2024273399 date "2010-01-29" @default.
• W2024273399 modified "2023-09-27" @default.
• W2024273399 title "Identification of Serum Biomarkers in End Stage Liver Disease" @default.
• W2024273399 cites W1558228229 @default.
• W2024273399 cites W159738587 @default.
• W2024273399 cites W1988759309 @default.
• W2024273399 cites W1991489334 @default.
• W2024273399 cites W1994908376 @default.
• W2024273399 cites W2000649393 @default.
• W2024273399 cites W2013716066 @default.
• W2024273399 cites W2025946383 @default.
• W2024273399 cites W2032817476 @default.
• W2024273399 cites W2048027700 @default.
• W2024273399 cites W2056082570 @default.
• W2024273399 cites W2073861708 @default.
• W2024273399 cites W2083410657 @default.
• W2024273399 cites W2085071775 @default.
• W2024273399 cites W2097055679 @default.
• W2024273399 cites W2115567902 @default.
• W2024273399 cites W2117145345 @default.
• W2024273399 cites W2140472284 @default.
• W2024273399 cites W2143164727 @default.
• W2024273399 cites W2151769300 @default.
• W2024273399 cites W2162688319 @default.
• W2024273399 cites W2366456785 @default.
• W2024273399 cites W2474152840 @default.
• W2024273399 doi "https://doi.org/10.2174/1875318301003010001" @default.
• W2024273399 hasPublicationYear "2010" @default.
• W2024273399 type Work @default.
• W2024273399 sameAs 2024273399 @default.
• W2024273399 citedByCount "5" @default.
• W2024273399 countsByYear W20242733992013 @default.
• W2024273399 countsByYear W20242733992014 @default.
• W2024273399 countsByYear W20242733992022 @default.
• W2024273399 countsByYear W20242733992023 @default.
• W2024273399 crossrefType "journal-article" @default.
• W2024273399 hasAuthorship W2024273399A5022883772 @default.
• W2024273399 hasAuthorship W2024273399A5030435077 @default.
• W2024273399 hasAuthorship W2024273399A5033962588 @default.
• W2024273399 hasAuthorship W2024273399A5059680705 @default.
• W2024273399 hasAuthorship W2024273399A5067214484 @default.
• W2024273399 hasAuthorship W2024273399A5090787460 @default.
• W2024273399 hasBestOaLocation W20242733991 @default.
• W2024273399 hasConcept C126322002 @default.
• W2024273399 hasConcept C142724271 @default.
• W2024273399 hasConcept C146357865 @default.
• W2024273399 hasConcept C151730666 @default.
• W2024273399 hasConcept C2775934546 @default.
• W2024273399 hasConcept C2777075537 @default.
• W2024273399 hasConcept C2777214474 @default.
• W2024273399 hasConcept C2777575235 @default.
• W2024273399 hasConcept C2777766500 @default.
• W2024273399 hasConcept C2778772119 @default.
• W2024273399 hasConcept C2779134260 @default.
• W2024273399 hasConcept C2780559512 @default.
• W2024273399 hasConcept C2780732942 @default.
• W2024273399 hasConcept C71924100 @default.
• W2024273399 hasConcept C86803240 @default.
• W2024273399 hasConcept C90924648 @default.
• W2024273399 hasConceptScore W2024273399C126322002 @default.
• W2024273399 hasConceptScore W2024273399C142724271 @default.
• W2024273399 hasConceptScore W2024273399C146357865 @default.
• W2024273399 hasConceptScore W2024273399C151730666 @default.
• W2024273399 hasConceptScore W2024273399C2775934546 @default.
• W2024273399 hasConceptScore W2024273399C2777075537 @default.
• W2024273399 hasConceptScore W2024273399C2777214474 @default.
• W2024273399 hasConceptScore W2024273399C2777575235 @default.
• W2024273399 hasConceptScore W2024273399C2777766500 @default.
• W2024273399 hasConceptScore W2024273399C2778772119 @default.
• W2024273399 hasConceptScore W2024273399C2779134260 @default.
• W2024273399 hasConceptScore W2024273399C2780559512 @default.
• W2024273399 hasConceptScore W2024273399C2780732942 @default.
• W2024273399 hasConceptScore W2024273399C71924100 @default.
• W2024273399 hasConceptScore W2024273399C86803240 @default.
• W2024273399 hasConceptScore W2024273399C90924648 @default.
• W2024273399 hasIssue "1" @default.
• W2024273399 hasLocation W20242733991 @default.
• W2024273399 hasOpenAccess W2024273399 @default.
• W2024273399 hasPrimaryLocation W20242733991 @default.
• W2024273399 hasRelatedWork W1977012152 @default.
• W2024273399 hasRelatedWork W2016849191 @default.
• W2024273399 hasRelatedWork W2034927238 @default.
• W2024273399 hasRelatedWork W2104682956 @default.
• W2024273399 hasRelatedWork W2107697606 @default.
• W2024273399 hasRelatedWork W2153568700 @default.
• W2024273399 hasRelatedWork W2425737386 @default.
• W2024273399 hasRelatedWork W2738275677 @default.
• W2024273399 hasRelatedWork W2955053591 @default.
• W2024273399 hasRelatedWork W3028283160 @default.
• W2024273399 hasVolume "3" @default.

• next