Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024277315> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2024277315 endingPage "323" @default.
- W2024277315 startingPage "321" @default.
- W2024277315 abstract "The purpose of this study is to assess orally-disintegrating (OD) tablet of clonidine hydrochloride (CL) for a pre-operative sedation in pediatric surgery. Sedation score and plasma CL concentration of OD formulation was compared with original preparation, CL lollipop, in pediatric patients. Fourteen patients (age: 3.9±2.3 years, weight: 16.9±5.0 kg) for OD group and 9 patients (age: 4.4±3.1 years, weight: 17.2±7.0 kg) for lollipop group received 4 μg/kg of CL preparation. Pre-operative sedation was evaluated by 5-point scoring systems at entering the operating room. Plasma CL concentrations were determined 120 min after administration of CL preparation. The changes in systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR) were also assessed before and after administration of CL preparation. Every patients in OD group had satisfactory sedation (sedation score: 2 and 3), whereas, 3 (33%) in lollipop group had unsatisfactory sedation (sedation score: 0 and 1). Plasma CL concentration in OD group was significantly higher than those in lollipop group (0.75±0.15 vs. 0.42±0.21 ng/ml, p<0.01). There was no significant difference in hemodynamic parameters (SBP, DBP and HR) between before and after administration of CL preparation in both OD and lollipop group. We conclude that OD is superior preparation of CL for pre-operative sedation in pediatric surgery." @default.
- W2024277315 created "2016-06-24" @default.
- W2024277315 creator A5024830154 @default.
- W2024277315 creator A5035016541 @default.
- W2024277315 creator A5056184076 @default.
- W2024277315 creator A5072105975 @default.
- W2024277315 creator A5084498942 @default.
- W2024277315 date "2006-01-01" @default.
- W2024277315 modified "2023-10-02" @default.
- W2024277315 title "Assessment of Clonidine Orally Disintegrating Tablet for Pre-anesthetic Medication in Pediatric Surgery" @default.
- W2024277315 cites W1969822824 @default.
- W2024277315 cites W1999776567 @default.
- W2024277315 cites W2017540087 @default.
- W2024277315 cites W2031548172 @default.
- W2024277315 cites W2036862004 @default.
- W2024277315 cites W2074291836 @default.
- W2024277315 cites W2094370798 @default.
- W2024277315 cites W2095388594 @default.
- W2024277315 cites W2115628342 @default.
- W2024277315 cites W2170777806 @default.
- W2024277315 cites W2267546757 @default.
- W2024277315 cites W4241462411 @default.
- W2024277315 doi "https://doi.org/10.1248/bpb.29.321" @default.
- W2024277315 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16462039" @default.
- W2024277315 hasPublicationYear "2006" @default.
- W2024277315 type Work @default.
- W2024277315 sameAs 2024277315 @default.
- W2024277315 citedByCount "5" @default.
- W2024277315 countsByYear W20242773152012 @default.
- W2024277315 countsByYear W20242773152016 @default.
- W2024277315 countsByYear W20242773152023 @default.
- W2024277315 crossrefType "journal-article" @default.
- W2024277315 hasAuthorship W2024277315A5024830154 @default.
- W2024277315 hasAuthorship W2024277315A5035016541 @default.
- W2024277315 hasAuthorship W2024277315A5056184076 @default.
- W2024277315 hasAuthorship W2024277315A5072105975 @default.
- W2024277315 hasAuthorship W2024277315A5084498942 @default.
- W2024277315 hasBestOaLocation W20242773151 @default.
- W2024277315 hasConcept C126322002 @default.
- W2024277315 hasConcept C2776814716 @default.
- W2024277315 hasConcept C2777953023 @default.
- W2024277315 hasConcept C2778399450 @default.
- W2024277315 hasConcept C42219234 @default.
- W2024277315 hasConcept C71924100 @default.
- W2024277315 hasConcept C84393581 @default.
- W2024277315 hasConceptScore W2024277315C126322002 @default.
- W2024277315 hasConceptScore W2024277315C2776814716 @default.
- W2024277315 hasConceptScore W2024277315C2777953023 @default.
- W2024277315 hasConceptScore W2024277315C2778399450 @default.
- W2024277315 hasConceptScore W2024277315C42219234 @default.
- W2024277315 hasConceptScore W2024277315C71924100 @default.
- W2024277315 hasConceptScore W2024277315C84393581 @default.
- W2024277315 hasIssue "2" @default.
- W2024277315 hasLocation W20242773151 @default.
- W2024277315 hasLocation W20242773152 @default.
- W2024277315 hasOpenAccess W2024277315 @default.
- W2024277315 hasPrimaryLocation W20242773151 @default.
- W2024277315 hasRelatedWork W1593783008 @default.
- W2024277315 hasRelatedWork W1864032968 @default.
- W2024277315 hasRelatedWork W1894855081 @default.
- W2024277315 hasRelatedWork W1999079648 @default.
- W2024277315 hasRelatedWork W2185099433 @default.
- W2024277315 hasRelatedWork W2237515816 @default.
- W2024277315 hasRelatedWork W4235433908 @default.
- W2024277315 hasRelatedWork W4250939884 @default.
- W2024277315 hasRelatedWork W4289531850 @default.
- W2024277315 hasRelatedWork W2182668243 @default.
- W2024277315 hasVolume "29" @default.
- W2024277315 isParatext "false" @default.
- W2024277315 isRetracted "false" @default.
- W2024277315 magId "2024277315" @default.
- W2024277315 workType "article" @default.