FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024281310> ?p ?o ?g. }

• W2024281310 endingPage "163" @default.
• W2024281310 startingPage "158" @default.
• W2024281310 abstract "<b><i>Background/Aims:</i></b> The efficacy of both Infliximab (IFX) and Adalimumab (ADA) can be reduced over time. The aim of this study was to analyze the incidence of loss of efficacy (LOE) of both IFX and ADA, and outline the influence of disease duration on its occurrence. <b><i>Methods:</i></b> Retrospective, multicenter, observational cohort study, with CD patients treated with anti-TNF therapy. LOE was defined as the need for steroids, occurrence of major abdominal surgery during treatment, dose increase, interval shortening or switching of the anti-TNF agent. Patients were allocated in three subgroups based on disease duration (DD): <24 months, between 24 and 60 months and >60 months. <b><i>Results:</i></b> 175 patients were included in the study (117 under IFX and 58 under ADA therapy). LOE occurred in 32% of patients with DD <24 months, in 33.3% with DD between 24 and 60 months and in 31.3% of subjects with DD over 60 months (p = 0.975). <b><i>Conclusions:</i></b> Disease duration (DD) did not influence LOE rates. These results suggest that in real-world observational practice, patients with early CD might have the same rates of LOE than patients with a disease prolonging for a longer duration." @default.
• W2024281310 created "2016-06-24" @default.
• W2024281310 creator A5004247207 @default.
• W2024281310 creator A5006706518 @default.
• W2024281310 creator A5020756972 @default.
• W2024281310 creator A5026438817 @default.
• W2024281310 creator A5028899347 @default.
• W2024281310 creator A5030834840 @default.
• W2024281310 creator A5039351957 @default.
• W2024281310 creator A5072336237 @default.
• W2024281310 creator A5087271151 @default.
• W2024281310 date "2015-01-01" @default.
• W2024281310 modified "2023-10-16" @default.
• W2024281310 title "Disease Duration Did Not Influence the Rates of Loss of Efficacy of the Anti-TNF Therapy in Latin American Crohn's Disease Patients" @default.
• W2024281310 cites W1966282130 @default.
• W2024281310 cites W1973085101 @default.
• W2024281310 cites W1979196222 @default.
• W2024281310 cites W1983254671 @default.
• W2024281310 cites W1991810959 @default.
• W2024281310 cites W2003904406 @default.
• W2024281310 cites W2004707122 @default.
• W2024281310 cites W2008497900 @default.
• W2024281310 cites W2017149988 @default.
• W2024281310 cites W2025549389 @default.
• W2024281310 cites W2030638161 @default.
• W2024281310 cites W2035863637 @default.
• W2024281310 cites W2072640801 @default.
• W2024281310 cites W2121569640 @default.
• W2024281310 cites W2126807394 @default.
• W2024281310 cites W2137775651 @default.
• W2024281310 cites W2145436896 @default.
• W2024281310 cites W2152026434 @default.
• W2024281310 cites W2166771071 @default.
• W2024281310 cites W2168370388 @default.
• W2024281310 cites W2171341132 @default.
• W2024281310 doi "https://doi.org/10.1159/000371655" @default.
• W2024281310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25721295" @default.
• W2024281310 hasPublicationYear "2015" @default.
• W2024281310 type Work @default.
• W2024281310 sameAs 2024281310 @default.
• W2024281310 citedByCount "6" @default.
• W2024281310 countsByYear W20242813102017 @default.
• W2024281310 countsByYear W20242813102019 @default.
• W2024281310 countsByYear W20242813102020 @default.
• W2024281310 countsByYear W20242813102022 @default.
• W2024281310 crossrefType "journal-article" @default.
• W2024281310 hasAuthorship W2024281310A5004247207 @default.
• W2024281310 hasAuthorship W2024281310A5006706518 @default.
• W2024281310 hasAuthorship W2024281310A5020756972 @default.
• W2024281310 hasAuthorship W2024281310A5026438817 @default.
• W2024281310 hasAuthorship W2024281310A5028899347 @default.
• W2024281310 hasAuthorship W2024281310A5030834840 @default.
• W2024281310 hasAuthorship W2024281310A5039351957 @default.
• W2024281310 hasAuthorship W2024281310A5072336237 @default.
• W2024281310 hasAuthorship W2024281310A5087271151 @default.
• W2024281310 hasConcept C120665830 @default.
• W2024281310 hasConcept C121332964 @default.
• W2024281310 hasConcept C126322002 @default.
• W2024281310 hasConcept C141071460 @default.
• W2024281310 hasConcept C167135981 @default.
• W2024281310 hasConcept C23131810 @default.
• W2024281310 hasConcept C2777138892 @default.
• W2024281310 hasConcept C2779134260 @default.
• W2024281310 hasConcept C2779280984 @default.
• W2024281310 hasConcept C2780132546 @default.
• W2024281310 hasConcept C61511704 @default.
• W2024281310 hasConcept C71924100 @default.
• W2024281310 hasConcept C90924648 @default.
• W2024281310 hasConceptScore W2024281310C120665830 @default.
• W2024281310 hasConceptScore W2024281310C121332964 @default.
• W2024281310 hasConceptScore W2024281310C126322002 @default.
• W2024281310 hasConceptScore W2024281310C141071460 @default.
• W2024281310 hasConceptScore W2024281310C167135981 @default.
• W2024281310 hasConceptScore W2024281310C23131810 @default.
• W2024281310 hasConceptScore W2024281310C2777138892 @default.
• W2024281310 hasConceptScore W2024281310C2779134260 @default.
• W2024281310 hasConceptScore W2024281310C2779280984 @default.
• W2024281310 hasConceptScore W2024281310C2780132546 @default.
• W2024281310 hasConceptScore W2024281310C61511704 @default.
• W2024281310 hasConceptScore W2024281310C71924100 @default.
• W2024281310 hasConceptScore W2024281310C90924648 @default.
• W2024281310 hasIssue "2" @default.
• W2024281310 hasLocation W20242813101 @default.
• W2024281310 hasLocation W20242813102 @default.
• W2024281310 hasOpenAccess W2024281310 @default.
• W2024281310 hasPrimaryLocation W20242813101 @default.
• W2024281310 hasRelatedWork W2006318665 @default.
• W2024281310 hasRelatedWork W2006812737 @default.
• W2024281310 hasRelatedWork W2034536484 @default.
• W2024281310 hasRelatedWork W2121804659 @default.
• W2024281310 hasRelatedWork W2130668816 @default.
• W2024281310 hasRelatedWork W2131408481 @default.
• W2024281310 hasRelatedWork W2331617350 @default.
• W2024281310 hasRelatedWork W2525802576 @default.
• W2024281310 hasRelatedWork W3092204953 @default.
• W2024281310 hasRelatedWork W3184875481 @default.
• W2024281310 hasVolume "91" @default.
• W2024281310 isParatext "false" @default.

• next