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• W2024297892 abstract "Tetrachlorido(O,O′-dibutyl-ethylenediamine-N,N′-di-3-propionate)platinum(iv) complex, [PtCl4(n-Bu2eddp)], was previously found to be effective against fibrosarcoma and glioma cell lines. Here we presented that [PtCl4(n-Bu2eddp)] strongly reduced the growth of B16 melanoma cells in vitro. Inhibition of cell viability was accompanied with induction of both necrotic and apoptotic cell death. In addition, [PtCl4(n-Bu2eddp)] concealed the expansion of tumors induced in syngeneic C57Bl/6 mice without visible signs of nephrotoxicity." @default.
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• W2024297892 date "2012-01-01" @default.
• W2024297892 modified "2023-10-18" @default.
• W2024297892 title "Melanoma tumor inhibition by tetrachlorido(O,O′-dibutyl-ethylenediamine-N,N′-di-3-propionate)platinum(iv) complex: in vitro and in vivo investigations" @default.
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• W2024297892 doi "https://doi.org/10.1039/c2mt20150j" @default.
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