FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024298957> ?p ?o ?g. }

• W2024298957 endingPage "560" @default.
• W2024298957 startingPage "553" @default.
• W2024298957 abstract "Ketone bodies have been regarded as an energy source that is mainly produced in the liver, and exported to extrahepatic tissues. However, ketone bodies have also been suggested to be used during the lipogenesis by the ketone body-utilizing enzyme, acetoacetyl-CoA synthetase (AACS). To elucidate the physiological role of AACS in the liver, we investigated the mechanism of transcription of the AACS gene and performed knockdown experiments. We showed that SREBP-2 regulates the expression of AACS and that knockdown of AACS in vivo, by the hydrodynamics method, resulted in the reduction of total blood cholesterol. These results suggest that ketone body metabolism via AACS activity plays an important role in cholesterol homeostasis." @default.
• W2024298957 created "2016-06-24" @default.
• W2024298957 creator A5019962809 @default.
• W2024298957 creator A5021837954 @default.
• W2024298957 creator A5054538535 @default.
• W2024298957 creator A5072628472 @default.
• W2024298957 creator A5076993537 @default.
• W2024298957 creator A5087404732 @default.
• W2024298957 date "2012-11-01" @default.
• W2024298957 modified "2023-09-30" @default.
• W2024298957 title "Acetoacetyl-CoA synthetase, a ketone body-utilizing enzyme, is controlled by SREBP-2 and affects serum cholesterol levels" @default.
• W2024298957 cites W1502473233 @default.
• W2024298957 cites W1576878402 @default.
• W2024298957 cites W1828717405 @default.
• W2024298957 cites W1971876285 @default.
• W2024298957 cites W1976735635 @default.
• W2024298957 cites W1977737090 @default.
• W2024298957 cites W2006454401 @default.
• W2024298957 cites W2009616432 @default.
• W2024298957 cites W2027611302 @default.
• W2024298957 cites W2028874440 @default.
• W2024298957 cites W2033283984 @default.
• W2024298957 cites W2038655486 @default.
• W2024298957 cites W2039999119 @default.
• W2024298957 cites W2064318855 @default.
• W2024298957 cites W2088545470 @default.
• W2024298957 cites W2091330563 @default.
• W2024298957 cites W2091463500 @default.
• W2024298957 cites W2114445980 @default.
• W2024298957 cites W2136558879 @default.
• W2024298957 cites W2138486337 @default.
• W2024298957 cites W2320147764 @default.
• W2024298957 cites W2357597734 @default.
• W2024298957 doi "https://doi.org/10.1016/j.ymgme.2012.08.017" @default.
• W2024298957 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22985732" @default.
• W2024298957 hasPublicationYear "2012" @default.
• W2024298957 type Work @default.
• W2024298957 sameAs 2024298957 @default.
• W2024298957 citedByCount "38" @default.
• W2024298957 countsByYear W20242989572012 @default.
• W2024298957 countsByYear W20242989572013 @default.
• W2024298957 countsByYear W20242989572014 @default.
• W2024298957 countsByYear W20242989572015 @default.
• W2024298957 countsByYear W20242989572016 @default.
• W2024298957 countsByYear W20242989572017 @default.
• W2024298957 countsByYear W20242989572018 @default.
• W2024298957 countsByYear W20242989572019 @default.
• W2024298957 countsByYear W20242989572020 @default.
• W2024298957 countsByYear W20242989572021 @default.
• W2024298957 countsByYear W20242989572022 @default.
• W2024298957 countsByYear W20242989572023 @default.
• W2024298957 crossrefType "journal-article" @default.
• W2024298957 hasAuthorship W2024298957A5019962809 @default.
• W2024298957 hasAuthorship W2024298957A5021837954 @default.
• W2024298957 hasAuthorship W2024298957A5054538535 @default.
• W2024298957 hasAuthorship W2024298957A5072628472 @default.
• W2024298957 hasAuthorship W2024298957A5076993537 @default.
• W2024298957 hasAuthorship W2024298957A5087404732 @default.
• W2024298957 hasConcept C104317684 @default.
• W2024298957 hasConcept C126322002 @default.
• W2024298957 hasConcept C134018914 @default.
• W2024298957 hasConcept C141359234 @default.
• W2024298957 hasConcept C170493617 @default.
• W2024298957 hasConcept C173396325 @default.
• W2024298957 hasConcept C178790620 @default.
• W2024298957 hasConcept C181199279 @default.
• W2024298957 hasConcept C185592680 @default.
• W2024298957 hasConcept C2491326 @default.
• W2024298957 hasConcept C2777738585 @default.
• W2024298957 hasConcept C2778163477 @default.
• W2024298957 hasConcept C2778718757 @default.
• W2024298957 hasConcept C31532488 @default.
• W2024298957 hasConcept C4733338 @default.
• W2024298957 hasConcept C55493867 @default.
• W2024298957 hasConcept C62231903 @default.
• W2024298957 hasConcept C63645605 @default.
• W2024298957 hasConcept C71924100 @default.
• W2024298957 hasConcept C85051948 @default.
• W2024298957 hasConcept C86803240 @default.
• W2024298957 hasConceptScore W2024298957C104317684 @default.
• W2024298957 hasConceptScore W2024298957C126322002 @default.
• W2024298957 hasConceptScore W2024298957C134018914 @default.
• W2024298957 hasConceptScore W2024298957C141359234 @default.
• W2024298957 hasConceptScore W2024298957C170493617 @default.
• W2024298957 hasConceptScore W2024298957C173396325 @default.
• W2024298957 hasConceptScore W2024298957C178790620 @default.
• W2024298957 hasConceptScore W2024298957C181199279 @default.
• W2024298957 hasConceptScore W2024298957C185592680 @default.
• W2024298957 hasConceptScore W2024298957C2491326 @default.
• W2024298957 hasConceptScore W2024298957C2777738585 @default.
• W2024298957 hasConceptScore W2024298957C2778163477 @default.
• W2024298957 hasConceptScore W2024298957C2778718757 @default.
• W2024298957 hasConceptScore W2024298957C31532488 @default.
• W2024298957 hasConceptScore W2024298957C4733338 @default.
• W2024298957 hasConceptScore W2024298957C55493867 @default.
• W2024298957 hasConceptScore W2024298957C62231903 @default.
• W2024298957 hasConceptScore W2024298957C63645605 @default.
• W2024298957 hasConceptScore W2024298957C71924100 @default.

• next