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- W2024299685 abstract "A severe but unusual complication of sickle cell vaso-occlusive crisis is acute liver failure related to intrahepatic cholestasis. The outcome is usually fatal in adults. A case of reversible acute liver failure in a patient with s/β+ thalassemia is reported. The patient was admitted to the intensive care unit because of major organ failure related to vascular occlusion phenomena. After blood-plasma transfusion and supportive therapy for acute liver failure, complete recovery was noted. A liver biopsy performed at the stage of recovery was compatible with intrahepatic cholestasis and sickling. Even though patients with s/β+ thalassemia usually manifest milder symptoms, they rarely develop major organ failure such as acute liver failure." @default.
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- W2024299685 date "1996-06-01" @default.
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- W2024299685 title "Reversal of Liver Failure in Sickle Cell Vasa-Occlusive Crisis" @default.
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- W2024299685 doi "https://doi.org/10.1016/s0002-9629(15)41724-0" @default.
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