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- W2024301215 abstract "Glucose facilitated diffusion into cells depends on concentration gradients between intracellular and extracellular spaces and can be modified by several factors such as insulin and contractions. Calmodulin participates in the insulin induced recruitment of vesicles containing glucose transporter molecules and its inhibition by trifluoperazine blocks insulin increases in glucose uptake. In the present study we tested if calmodulin inhibition with trifluoperazine blocks hindlimb muscle glucose uptake increase induced by contractions. Trifluoperazine does not inhibit exercise induced increases in glucose uptake; therefore, the mechanisms by which insulin and functional activity increase glucose uptake are different." @default.
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- W2024301215 date "1994-01-01" @default.
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- W2024301215 title "Different mechanism for insulin induced and contraction induced increases in skeletal muscle glucose uptake" @default.
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- W2024301215 doi "https://doi.org/10.1016/0024-3205(94)90072-8" @default.
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