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- W2024302733 abstract "It is known that reticulocytes formed in animals in response to phenylhydrazine treatment have a shorter life span than those formed as a consequence of bleeding. The experiments presented illustrate that the reticulocytes formed consequent to the action of this drug exhibit membrane alterations, in the absence of intracellular oxidative changes (e.g., to hemoglobin), which might be expected to contribute to their decreased survival. These membrane alterations include the formation of flourescent chromolipids, a decrease in spectrin polypeptides, and an increase in high molecular weight membrane protein polymers. It is suggested that these effects are unique to the reticulocytes formed as a response to phenylhydrazine since they are a consequence of the peroxidation of membrane phospholipids initiated by this agent." @default.
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- W2024302733 date "1980-05-01" @default.
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- W2024302733 title "Membrane alterations in phenylhydrazine-induced reticulocytes" @default.
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- W2024302733 doi "https://doi.org/10.1016/0003-9861(80)90560-3" @default.
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