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• W2024303969 abstract "The effect of the Ca2+ entry blocker, verapamil, on the biosynthesis of cholesterol and the metabolism of low-density lipoprotein (LDL) was studied in cultured human monocyte-derived macrophages. Addition of verapamil (50 μM) of monocyte-derived macrophages enhanced 125I-LDL and 125I-labelled acetyl-LDL binding and internalization, and increased [2-14C]acetate incorporation into cholesterol. Since higher levels of LDL and modified lipoproteins may be implicated in atherogenesis, the more efficient processing of these lipoproteins by monocyte-derived macrophages in the presence of Ca2+ blocker warrants further assessment for its potential as an antiatherogenic agent." @default.
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• W2024303969 date "1985-10-01" @default.
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• W2024303969 title "Enhancement of cholesteryl ester metabolism in cultured human monocyte-derived macrophages by verapamil" @default.
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• W2024303969 doi "https://doi.org/10.1016/0167-4889(85)90155-7" @default.
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