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- W2024305502 startingPage "973" @default.
- W2024305502 abstract "A natural precursor (L) of streptomycin which had no antibiotic potency was obtained from mycelium suspension of Streptomyces griseus in glucose solution and was transformed to streptomycin by H enzyme obtained from mycelium of the organism. This transforming reaction was carried out most effectively at slightly alkaline pH and inhibited by inorganic phosphate and ethylenediaminetetraacetate. L component was considered to be a phosphorylated compound and liberation of the phosphoric acid was essential for L component to be transformed to streptomycin. This transformation was performed not only by H enzyme but also by intestinal alkaline phosphatase, although some difference in the reaction mechanism was supposed to be between those two enzymes." @default.
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- W2024305502 date "1967-01-01" @default.
- W2024305502 modified "2023-10-16" @default.
- W2024305502 title "Biosynthesis of Streptomycin" @default.
- W2024305502 doi "https://doi.org/10.1271/bbb1961.31.973" @default.
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