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• W2024315058 abstract "This article describes a systematic evaluation of factors affecting the stability of the performance of Harvard ambient fine-particle concentrators, an essential requirement for controlled animal and human exposure studies that utilize these technologies. Phenomenological problems during the operation of the concentrator, including pressure drop increase and decrease in concentration enrichment, were statistically correlated with ambient air parameters such as temperature, relative humidity, PM2.5 mass concentration, and mass median diameter. The normalized hourly pressure drop across the concentrator was strongly associated (R2 = .81) with the product of ambient PM2.5 mass concentration and the difference between the vapor pressure downstream of the impactor nozzle and the saturation vapor pressure at the adiabatic expansion temperature (i.e., the temperature of the aerosol immediately downstream of the virtual impactors). From multiple regression analysis, the average enrichment factor was predicted reasonably well (R2 = .67) by aerosol mass median diameter and the normalized hourly pressure drop. Based on these results, we can anticipate in any given day whether an exposure study can be conducted without a considerable increase in the concentrator pressure drop, which might lead to an abrupt or premature termination of the exposure. As particle mass concentration and ambient dewpoint are the two main parameters responsible for raising the pressure drop across the concentrator, efforts should be made to either desiccate the ambient aerosol at days of high dewpoints, or to dilute the ambient PM at days of high concentrations, prior to drawing the aerosol through the virtual impactors. The latter approach is recommended on days of severe ambient pollution conditions because it is simpler and also makes it possible to maintain the appropriate concentration level delivered to the exposure chamber." @default.
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• W2024315058 date "2000-01-01" @default.
• W2024315058 modified "2023-10-12" @default.
• W2024315058 title "FACTORS AFFECTING THE STABILITY OF THE PERFORMANCE OF AMBIENT FINE-PARTICLE CONCENTRATORS" @default.
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• W2024315058 doi "https://doi.org/10.1080/713856633" @default.
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