Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024333046> ?p ?o ?g. }
- W2024333046 endingPage "268" @default.
- W2024333046 startingPage "255" @default.
- W2024333046 abstract "1 Distension-sensitive vagal afferent fibres from the cardiac region of the guinea-pig stomach were recorded extracellularly, then filled with biotinamide, using an anterograde tracing technique. 2 Most of the stretch-sensitive units of the guinea-pig stomach (41 out of 47; number of animals N= 26) had low thresholds (less than 1 mm) to circumferential stretch and showed slow adaptation. Twenty of these units fired spontaneously under resting conditions (mean: 1.9 ± 0.3 Hz, n = 20, N = 14). 3 Adaptation of firing during slow or maintained stretch correlated closely with accommodation of intramural tension, but tension-independent adaptation was also present. 4 Nicardipine (3 μm) with hyoscine (3 μm) reduced stretch-evoked firing of gastric vagal afferents, by inhibiting smooth muscle contraction. Gadolinium (1 mm) blocked distension-evoked firing. 5 Focal stimulation of the stomach muscle wall with a von Frey hair (0.4 mN) identified one to six punctate receptive fields in each low threshold vagal distension-sensitive afferent. These were marked on the serosal surface of the stomach wall. 6 Anterograde filling of recorded nerve trunks revealed intraganglionic laminar endings (IGLEs) within 142 ± 34 μm (n = 38; N = 10) of marked receptive fields. The mean distance from randomly generated sites to the nearest IGLE was significantly greater (1500 ± 48 μm, n = 380, N = 10, P < 0.0001). Viscerofugal nerve cell bodies, intramuscular arrays and varicose axons were not associated with receptive fields. The results indicate that IGLEs are the mechanotransduction sites of low threshold, slowly adapting vagal tension receptors in the guinea-pig upper stomach." @default.
- W2024333046 created "2016-06-24" @default.
- W2024333046 creator A5018041871 @default.
- W2024333046 creator A5019583844 @default.
- W2024333046 creator A5060680366 @default.
- W2024333046 date "2001-07-01" @default.
- W2024333046 modified "2023-10-02" @default.
- W2024333046 title "Intraganglionic laminar endings are mechano‐transduction sites of vagal tension receptors in the guinea‐pig stomach" @default.
- W2024333046 cites W1492768290 @default.
- W2024333046 cites W1730174749 @default.
- W2024333046 cites W1766894222 @default.
- W2024333046 cites W1785565621 @default.
- W2024333046 cites W1873448316 @default.
- W2024333046 cites W1881994315 @default.
- W2024333046 cites W1889813556 @default.
- W2024333046 cites W1964145632 @default.
- W2024333046 cites W1967785035 @default.
- W2024333046 cites W1968408735 @default.
- W2024333046 cites W1971656425 @default.
- W2024333046 cites W1975019413 @default.
- W2024333046 cites W1976609043 @default.
- W2024333046 cites W1979177881 @default.
- W2024333046 cites W1985442485 @default.
- W2024333046 cites W1986871759 @default.
- W2024333046 cites W1990344472 @default.
- W2024333046 cites W1991540821 @default.
- W2024333046 cites W2000739658 @default.
- W2024333046 cites W2000956867 @default.
- W2024333046 cites W2014897517 @default.
- W2024333046 cites W2020215295 @default.
- W2024333046 cites W2024437801 @default.
- W2024333046 cites W2025224324 @default.
- W2024333046 cites W2030245254 @default.
- W2024333046 cites W2030916992 @default.
- W2024333046 cites W2031752928 @default.
- W2024333046 cites W2042664452 @default.
- W2024333046 cites W2046943511 @default.
- W2024333046 cites W2066118083 @default.
- W2024333046 cites W2068445454 @default.
- W2024333046 cites W2068670327 @default.
- W2024333046 cites W2085768687 @default.
- W2024333046 cites W2088388072 @default.
- W2024333046 cites W2088460577 @default.
- W2024333046 cites W2094186040 @default.
- W2024333046 cites W2095543699 @default.
- W2024333046 cites W2130500248 @default.
- W2024333046 cites W2155236015 @default.
- W2024333046 cites W2183653783 @default.
- W2024333046 cites W2184606226 @default.
- W2024333046 cites W2232115551 @default.
- W2024333046 cites W2273976413 @default.
- W2024333046 cites W2317520538 @default.
- W2024333046 cites W2334090634 @default.
- W2024333046 cites W2336852929 @default.
- W2024333046 cites W3139831453 @default.
- W2024333046 doi "https://doi.org/10.1111/j.1469-7793.2001.00255.x" @default.
- W2024333046 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2278677" @default.
- W2024333046 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11433006" @default.
- W2024333046 hasPublicationYear "2001" @default.
- W2024333046 type Work @default.
- W2024333046 sameAs 2024333046 @default.
- W2024333046 citedByCount "237" @default.
- W2024333046 countsByYear W20243330462012 @default.
- W2024333046 countsByYear W20243330462013 @default.
- W2024333046 countsByYear W20243330462014 @default.
- W2024333046 countsByYear W20243330462015 @default.
- W2024333046 countsByYear W20243330462016 @default.
- W2024333046 countsByYear W20243330462017 @default.
- W2024333046 countsByYear W20243330462018 @default.
- W2024333046 countsByYear W20243330462019 @default.
- W2024333046 countsByYear W20243330462020 @default.
- W2024333046 countsByYear W20243330462021 @default.
- W2024333046 countsByYear W20243330462022 @default.
- W2024333046 countsByYear W20243330462023 @default.
- W2024333046 crossrefType "journal-article" @default.
- W2024333046 hasAuthorship W2024333046A5018041871 @default.
- W2024333046 hasAuthorship W2024333046A5019583844 @default.
- W2024333046 hasAuthorship W2024333046A5060680366 @default.
- W2024333046 hasBestOaLocation W20243330461 @default.
- W2024333046 hasConcept C105702510 @default.
- W2024333046 hasConcept C126322002 @default.
- W2024333046 hasConcept C134018914 @default.
- W2024333046 hasConcept C169760540 @default.
- W2024333046 hasConcept C185592680 @default.
- W2024333046 hasConcept C19071747 @default.
- W2024333046 hasConcept C24998067 @default.
- W2024333046 hasConcept C2776625112 @default.
- W2024333046 hasConcept C2779422922 @default.
- W2024333046 hasConcept C2781404750 @default.
- W2024333046 hasConcept C2909127448 @default.
- W2024333046 hasConcept C71924100 @default.
- W2024333046 hasConcept C83974742 @default.
- W2024333046 hasConcept C86803240 @default.
- W2024333046 hasConceptScore W2024333046C105702510 @default.
- W2024333046 hasConceptScore W2024333046C126322002 @default.
- W2024333046 hasConceptScore W2024333046C134018914 @default.
- W2024333046 hasConceptScore W2024333046C169760540 @default.
- W2024333046 hasConceptScore W2024333046C185592680 @default.