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• W2024335572 abstract "<i>Background:</i> Patients with anorexia nervosa (AN) are at a high risk of renal failure. Chronic kidney disease (CKD) is often missed in these patients because the serum creatinine is a poor marker of kidney function. We studied the utility of cystatin C to detect renal failure in this population. <i>Method:</i> Twenty-seven AN patients were studied. Glomerular filtration rates (GFR) were measured with the chromium-51- ethylenediaminetetraacetate (⁵¹Cr-EDTA) method. We compared the ability of creatinine and cystatin C to detect stage 3 CKD (GFR below 60 ml/min) by ROC curve analysis. <i>Results:</i> In this cohort, there is no correlation between GFR and serum creatinine, but there is a significant correlation between cystatin C and GFR. By ROC analysis, the cystatin C concentration is better than the serum creatinine concentration for the detection of stage 3 CKD (area under the curve of 0.86 vs. 0.61, p = 0.05). <i>Conclusion:</i> Plasma cystatin C is better than serum creatinine in detecting stage 3 CKD in patients with AN." @default.
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• W2024335572 date "2008-10-27" @default.
• W2024335572 modified "2023-10-16" @default.
• W2024335572 title "Cystatin C or Creatinine for Detection of Stage 3 Chronic Kidney Disease in Anorexia Nervosa" @default.
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• W2024335572 doi "https://doi.org/10.1159/000166607" @default.
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