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• W2024349257 abstract "Abstract The formation of a novel type of hydrogel that combines chemically and physically crosslinked networks in a dual-network approach is presented here. Chitosan (CHT) and chondroitin sulfate (CS) were chemically modified with glycidyl methacrylate (GMA) and then crosslinked. The chemical hydrogels (CHT- and CS-gel) were deposited in different vials filled with CS or CHT stock solutions to form the dual-network hydrogels. FTIR, TGA and XRD analyses were used to characterize the chemical and the dual-network hydrogels. The percentages of CS or CHT complexed to the CHT- and CS-gel networks were calculated from the HPLC data. SEM images and swelling assays indicated that the formation of a secondary network by polyelectrolyte complexation changes the morphologies and liquid uptake capacities of the chemical hydrogels. Hence, the data and discussion presented here enable the formation of dual-network hydrogels with very interesting properties, such as the ability to interact with charged specimens (i.e., drugs, proteins or metal ions), a desirable feature for a wide range of applications." @default.
• W2024349257 created "2016-06-24" @default.
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• W2024349257 date "2013-12-01" @default.
• W2024349257 modified "2023-10-14" @default.
• W2024349257 title "Dual-network hydrogels based on chemically and physically crosslinked chitosan/chondroitin sulfate" @default.
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• W2024349257 doi "https://doi.org/10.1016/j.reactfunctpolym.2013.10.003" @default.
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