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• W2024351719 abstract "<h3>Objective</h3> This study aimed to estimate the prevalence and correlates of seropositivity to human papillomavirus (HPV)-16 in a subsample of adults who participated in the parent study <i>Epidemiology of Hepatitis C in the adult population of Puerto Rico (PR).</i> <h3>Setting</h3> The parent study was a population-based household survey aimed to estimate the seroprevalence of hepatitis C and other viral infections (hepatitis A, hepatitis B, HIV, and herpes simplex type 2) in PR (n=1654) between 2005 and 2008. <h3>Participants</h3> A subsample of the last 450 consecutive adults aged 21–64 years, recruited between February 2007 and January 2008, who participated in the parent study and agreed to participate in HPV testing. <h3>Primary and secondary outcome measures</h3> The samples were tested by ELISA for HPV-16 viral-like particle-specific immunoglobulin G. Information on sociodemographic, health, and lifestyle characteristics was collected. Logistic regression modelling was used to estimate the prevalence odds ratio (POR) to assess factors associated to HPV-16 seropositivity. <h3>Results</h3> Prevalence of seropositivity to HPV-16 was 11.3%. Seroprevalence was higher in women (15.8%) than men (5.6%; p=0.001). After adjusting for age and sex, ever smokers (POR 2.06, 95% CI 1.08 to 3.92) and participants with at least five lifetime sexual partners (POR 2.91, 95% CI 1.24 to 6.81) were more likely to be HPV-16 seropositive. <h3>Conclusions</h3> HPV-16 seropositivity is similar to that reported in the USA (10.4%) for NHANES 2003–2004 participants, although different assays were used in these studies. While future studies should evaluate HPV seroprevalence using a larger population-based sample, our results highlight the need to further understand the burden of HPV infection and HPV-related malignancies in PR, population with a low vaccine uptake." @default.
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• W2024351719 date "2014-02-01" @default.
• W2024351719 modified "2023-09-30" @default.
• W2024351719 title "Cross-sectional study of HPV-16 infection in a population-based subsample of Hispanic adults" @default.
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• W2024351719 doi "https://doi.org/10.1136/bmjopen-2013-004203" @default.
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