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- W2024352184 abstract "Synaptic vesicles are subcellular organelles that are found in the synaptic bouton and are responsible for the propagation of signals between neurons. Synaptic vesicles undergo endo- and exocytosis with the neuronal membrane to load and release neurotransmitters. Here we discuss how we utilize this property to load nanoparticles as a means of probing the interior of synaptic vesicles. To probe the intravesicular region of synaptic vesicles, we have developed a highly sensitive pH-sensing polymer dot. We feel the robust nature of the pH-sensing polymer dot will provide insight into the dynamics of proton loading into synaptic vesicles." @default.
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- W2024352184 date "2012-02-09" @default.
- W2024352184 modified "2023-09-23" @default.
- W2024352184 title "Probing the interior of synaptic vesicles with internalized nanoparticles" @default.
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- W2024352184 doi "https://doi.org/10.1117/12.905091" @default.
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