FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024353599> ?p ?o ?g. }

• W2024353599 endingPage "856" @default.
• W2024353599 startingPage "853" @default.
• W2024353599 abstract "Abnormal matrix metalloproteinase (MMP) activity and diastolic dysfunction may affect left ventricular (LV) remodeling and prognosis, but it is not known whether the combined evaluation of MMP-3 and MMP-9 and variables of diastolic dysfunction are useful for the risk stratification of patients with systolic heart failure (HF). Therefore, this study was designed to assess the value of combining circulating levels of MMPs and tissue Doppler measures of LV diastolic dysfunction to risk-stratify patients with systolic HF. Consecutive patients with systolic HF due to either ischemic or nonischemic cardiomyopathy (n = 134) and LV ejection fractions <45% were submitted to complete echocardiographic and Doppler examinations. The ratio of mitral E peak velocity and averaged e' velocity (E/e') was calculated. Plasma levels of MMP-3 and MMP-9 were measured at the time of index echocardiography. All-cause mortality was defined as the end point. The mean LV ejection fraction was 28 +/- 9%. There was a total of 32 deaths during follow-up (24 +/- 14 months). Several clinical, biochemical, Doppler, and echocardiographic parameters were associated with the outcome on univariate Cox regression analysis. After statistical adjustment for the potentially confounding factors by multivariate analysis, E/e' (hazard ratio 1.11, p = 0.0028), ejection fraction (hazard ratio 0.92, p = 0.017), and MMP-9 (hazard ratio 1.01, p = 0.027) remained significant independent predictors of the end point. Kaplan-Meier curves showed that survival was worse in patients with E/e' ratios >/=13 and MMP-9 levels >89.9 ng/mL (p <0.0001). In conclusion, the assessment of circulating MMP levels and tissue Doppler measures of LV diastolic dysfunction may improve the prognostic stratification of patients with systolic HF." @default.
• W2024353599 created "2016-06-24" @default.
• W2024353599 creator A5013736747 @default.
• W2024353599 creator A5025715284 @default.
• W2024353599 creator A5027821454 @default.
• W2024353599 creator A5032549678 @default.
• W2024353599 creator A5037536262 @default.
• W2024353599 creator A5047880986 @default.
• W2024353599 creator A5054968428 @default.
• W2024353599 creator A5089116480 @default.
• W2024353599 creator A5089714718 @default.
• W2024353599 date "2010-03-01" @default.
• W2024353599 modified "2023-10-04" @default.
• W2024353599 title "Circulating Matrix Metalloproteinase-3 and Metalloproteinase-9 and Tissue Doppler Measures of Diastolic Dysfunction to Risk Stratify Patients With Systolic Heart Failure" @default.
• W2024353599 cites W1967255096 @default.
• W2024353599 cites W1973819293 @default.
• W2024353599 cites W1986725788 @default.
• W2024353599 cites W1993804921 @default.
• W2024353599 cites W1996189549 @default.
• W2024353599 cites W1998914062 @default.
• W2024353599 cites W2004656949 @default.
• W2024353599 cites W2018670126 @default.
• W2024353599 cites W2041678973 @default.
• W2024353599 cites W2049997409 @default.
• W2024353599 cites W2058548032 @default.
• W2024353599 cites W2061663810 @default.
• W2024353599 cites W2093032251 @default.
• W2024353599 cites W2095106505 @default.
• W2024353599 cites W2095262035 @default.
• W2024353599 cites W2101099004 @default.
• W2024353599 cites W2112767296 @default.
• W2024353599 cites W2115222860 @default.
• W2024353599 cites W2117877435 @default.
• W2024353599 cites W2130162835 @default.
• W2024353599 cites W2141228550 @default.
• W2024353599 cites W2145573332 @default.
• W2024353599 cites W2149376322 @default.
• W2024353599 cites W2152003312 @default.
• W2024353599 cites W2164391136 @default.
• W2024353599 cites W3022179669 @default.
• W2024353599 doi "https://doi.org/10.1016/j.amjcard.2009.11.038" @default.
• W2024353599 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20211331" @default.
• W2024353599 hasPublicationYear "2010" @default.
• W2024353599 type Work @default.
• W2024353599 sameAs 2024353599 @default.
• W2024353599 citedByCount "35" @default.
• W2024353599 countsByYear W20243535992012 @default.
• W2024353599 countsByYear W20243535992013 @default.
• W2024353599 countsByYear W20243535992014 @default.
• W2024353599 countsByYear W20243535992015 @default.
• W2024353599 countsByYear W20243535992016 @default.
• W2024353599 countsByYear W20243535992017 @default.
• W2024353599 countsByYear W20243535992018 @default.
• W2024353599 countsByYear W20243535992019 @default.
• W2024353599 countsByYear W20243535992020 @default.
• W2024353599 countsByYear W20243535992021 @default.
• W2024353599 countsByYear W20243535992022 @default.
• W2024353599 crossrefType "journal-article" @default.
• W2024353599 hasAuthorship W2024353599A5013736747 @default.
• W2024353599 hasAuthorship W2024353599A5025715284 @default.
• W2024353599 hasAuthorship W2024353599A5027821454 @default.
• W2024353599 hasAuthorship W2024353599A5032549678 @default.
• W2024353599 hasAuthorship W2024353599A5037536262 @default.
• W2024353599 hasAuthorship W2024353599A5047880986 @default.
• W2024353599 hasAuthorship W2024353599A5054968428 @default.
• W2024353599 hasAuthorship W2024353599A5089116480 @default.
• W2024353599 hasAuthorship W2024353599A5089714718 @default.
• W2024353599 hasConcept C126322002 @default.
• W2024353599 hasConcept C144301174 @default.
• W2024353599 hasConcept C164705383 @default.
• W2024353599 hasConcept C207103383 @default.
• W2024353599 hasConcept C2778198053 @default.
• W2024353599 hasConcept C2780346441 @default.
• W2024353599 hasConcept C38180746 @default.
• W2024353599 hasConcept C44249647 @default.
• W2024353599 hasConcept C50382708 @default.
• W2024353599 hasConcept C57900726 @default.
• W2024353599 hasConcept C71924100 @default.
• W2024353599 hasConcept C78085059 @default.
• W2024353599 hasConcept C84393581 @default.
• W2024353599 hasConceptScore W2024353599C126322002 @default.
• W2024353599 hasConceptScore W2024353599C144301174 @default.
• W2024353599 hasConceptScore W2024353599C164705383 @default.
• W2024353599 hasConceptScore W2024353599C207103383 @default.
• W2024353599 hasConceptScore W2024353599C2778198053 @default.
• W2024353599 hasConceptScore W2024353599C2780346441 @default.
• W2024353599 hasConceptScore W2024353599C38180746 @default.
• W2024353599 hasConceptScore W2024353599C44249647 @default.
• W2024353599 hasConceptScore W2024353599C50382708 @default.
• W2024353599 hasConceptScore W2024353599C57900726 @default.
• W2024353599 hasConceptScore W2024353599C71924100 @default.
• W2024353599 hasConceptScore W2024353599C78085059 @default.
• W2024353599 hasConceptScore W2024353599C84393581 @default.
• W2024353599 hasIssue "6" @default.
• W2024353599 hasLocation W20243535991 @default.
• W2024353599 hasLocation W20243535992 @default.
• W2024353599 hasOpenAccess W2024353599 @default.
• W2024353599 hasPrimaryLocation W20243535991 @default.

• next