FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024357543> ?p ?o ?g. }

• W2024357543 endingPage "714" @default.
• W2024357543 startingPage "709" @default.
• W2024357543 abstract "The effect of 1 alpha,25-dihydroxyvitamin D3 [1 alpha,25-(OH)2-D3] on the proliferation and morphologic and biochemical differentiation of cultured human epidermal keratinocytes grown under defined, serum-free conditions was studied. 1 alpha,25-(OH)2-D3 caused a dose-dependent decrease in proliferation and an increase in the morphologic differentiation of human cultured keratinocytes. The number of attached basal cells decreased when exposed to 1 alpha,25-(OH)2-D3, whereas the number of attached squamous cells, terminally differentiated desquamated cells, and cornified cells increased concurrently. In addition, after incubation with 1 alpha,25-(OH)2-D3, there was a shift to cells of lighter density. In conjunction with its effect on the basal cells, 1 alpha,25-(OH)2-D3 resulted in an inhibition of DNA synthesis. The activity of transglutaminase, the enzyme responsible for cross-linking the proteins of the cornified envelope, was stimulated by 156% with 1 alpha,25-(OH)2-D3, but not with 1 beta,25-(OH)2-D3, a biologically inert isomer. Therefore it appears that 1 alpha,25-(OH)2-D3 is a potent inhibitor of keratinocyte proliferation as well as a stimulator of epidermal terminal differentiation." @default.
• W2024357543 created "2016-06-24" @default.
• W2024357543 creator A5046775144 @default.
• W2024357543 creator A5059633854 @default.
• W2024357543 creator A5087384896 @default.
• W2024357543 date "1986-06-01" @default.
• W2024357543 modified "2023-09-24" @default.
• W2024357543 title "Effect of 1α,25-Dihydroxyvitamin D3 on the Morphologic and Biochemical Differentiation of Cultured Human Epidermal Keratinocytes Grown in Serum-Free Conditions" @default.
• W2024357543 cites W1497338732 @default.
• W2024357543 cites W1538990103 @default.
• W2024357543 cites W1580094463 @default.
• W2024357543 cites W1748624304 @default.
• W2024357543 cites W1775749144 @default.
• W2024357543 cites W1906197854 @default.
• W2024357543 cites W1983851236 @default.
• W2024357543 cites W1989468162 @default.
• W2024357543 cites W1997429630 @default.
• W2024357543 cites W2003575314 @default.
• W2024357543 cites W2020574771 @default.
• W2024357543 cites W2030627408 @default.
• W2024357543 cites W2031689439 @default.
• W2024357543 cites W2038085058 @default.
• W2024357543 cites W2045934824 @default.
• W2024357543 cites W2046514203 @default.
• W2024357543 cites W2049043712 @default.
• W2024357543 cites W2053175261 @default.
• W2024357543 cites W2054480906 @default.
• W2024357543 cites W2100837269 @default.
• W2024357543 cites W2115941959 @default.
• W2024357543 cites W2161229567 @default.
• W2024357543 cites W2167132436 @default.
• W2024357543 doi "https://doi.org/10.1111/1523-1747.ep12276343" @default.
• W2024357543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2423618" @default.
• W2024357543 hasPublicationYear "1986" @default.
• W2024357543 type Work @default.
• W2024357543 sameAs 2024357543 @default.
• W2024357543 citedByCount "442" @default.
• W2024357543 countsByYear W20243575432012 @default.
• W2024357543 countsByYear W20243575432013 @default.
• W2024357543 countsByYear W20243575432014 @default.
• W2024357543 countsByYear W20243575432015 @default.
• W2024357543 countsByYear W20243575432016 @default.
• W2024357543 countsByYear W20243575432017 @default.
• W2024357543 countsByYear W20243575432018 @default.
• W2024357543 countsByYear W20243575432019 @default.
• W2024357543 countsByYear W20243575432020 @default.
• W2024357543 countsByYear W20243575432021 @default.
• W2024357543 countsByYear W20243575432022 @default.
• W2024357543 countsByYear W20243575432023 @default.
• W2024357543 crossrefType "journal-article" @default.
• W2024357543 hasAuthorship W2024357543A5046775144 @default.
• W2024357543 hasAuthorship W2024357543A5059633854 @default.
• W2024357543 hasAuthorship W2024357543A5087384896 @default.
• W2024357543 hasConcept C104317684 @default.
• W2024357543 hasConcept C134018914 @default.
• W2024357543 hasConcept C148738053 @default.
• W2024357543 hasConcept C153911025 @default.
• W2024357543 hasConcept C159110408 @default.
• W2024357543 hasConcept C185592680 @default.
• W2024357543 hasConcept C202751555 @default.
• W2024357543 hasConcept C25642318 @default.
• W2024357543 hasConcept C2775944032 @default.
• W2024357543 hasConcept C2777074287 @default.
• W2024357543 hasConcept C2778024521 @default.
• W2024357543 hasConcept C2779306644 @default.
• W2024357543 hasConcept C49453240 @default.
• W2024357543 hasConcept C55493867 @default.
• W2024357543 hasConcept C64241487 @default.
• W2024357543 hasConcept C64943373 @default.
• W2024357543 hasConcept C71924100 @default.
• W2024357543 hasConcept C86803240 @default.
• W2024357543 hasConceptScore W2024357543C104317684 @default.
• W2024357543 hasConceptScore W2024357543C134018914 @default.
• W2024357543 hasConceptScore W2024357543C148738053 @default.
• W2024357543 hasConceptScore W2024357543C153911025 @default.
• W2024357543 hasConceptScore W2024357543C159110408 @default.
• W2024357543 hasConceptScore W2024357543C185592680 @default.
• W2024357543 hasConceptScore W2024357543C202751555 @default.
• W2024357543 hasConceptScore W2024357543C25642318 @default.
• W2024357543 hasConceptScore W2024357543C2775944032 @default.
• W2024357543 hasConceptScore W2024357543C2777074287 @default.
• W2024357543 hasConceptScore W2024357543C2778024521 @default.
• W2024357543 hasConceptScore W2024357543C2779306644 @default.
• W2024357543 hasConceptScore W2024357543C49453240 @default.
• W2024357543 hasConceptScore W2024357543C55493867 @default.
• W2024357543 hasConceptScore W2024357543C64241487 @default.
• W2024357543 hasConceptScore W2024357543C64943373 @default.
• W2024357543 hasConceptScore W2024357543C71924100 @default.
• W2024357543 hasConceptScore W2024357543C86803240 @default.
• W2024357543 hasIssue "6" @default.
• W2024357543 hasLocation W20243575431 @default.
• W2024357543 hasLocation W20243575432 @default.
• W2024357543 hasOpenAccess W2024357543 @default.
• W2024357543 hasPrimaryLocation W20243575431 @default.
• W2024357543 hasRelatedWork W1512661814 @default.
• W2024357543 hasRelatedWork W1974725462 @default.
• W2024357543 hasRelatedWork W1974759387 @default.
• W2024357543 hasRelatedWork W2004662140 @default.

• next