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- W2024358624 abstract "Abstract Objective To differentiate cystic and cylindrical bronchiectasis utilizing a diagnostic triad of HRCT score, PFTs, and echocardiography. Design A prospective observational cross sectional study. Setting All bronchiectasis patients admitted to the chest department of Assiut and Al-Azhar Universities from May 2012 to June 2014 were enrolled in this study. Main outcome measures HRCT score, pulmonary function tests parameters (FEV1, FEV1/FVC, FVC, PaO 2 , PaCO 2 and DLCO) and complete echocardiographic assessment were done for all patients. Results Obstructive pulmonary defect was observed in a majority of patients (56%). FVC%, FEV1 and FEV1/FVC were lower in patients with cylindrical as compared to cystic bronchiectasis. RV diameter was significantly greater in cystic bronchiectasis, and was positively correlated with pulmonary hypertension and negatively correlated with PaO 2 . PH was significantly greater in patients with cystic bronchiectasis and was positively correlated with PaCO 2 , and inversely correlated with PaO 2 , and FEV1. Global HRCT scores for cystic bronchiectasis were significantly correlated with the values of FEV1% and with SPAP. Conclusions Cystic bronchiectasis is associated with more severe lung function impairment and worse HRCT scores as compared with cylindrical bronchiectasis. In cystic bronchiectasis, HRCT scores correlated with FEV1% and SPAP and could be a predictor of future PH. HRCT depicts these pathological changes, moreover, high HRCT score not only reflects lung damage in those patients, but it can also be correlated with PH. PH; therefore can be a marker of lung damage in bronchiectatic patients." @default.
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- W2024358624 date "2015-04-01" @default.
- W2024358624 modified "2023-09-27" @default.
- W2024358624 title "Role of a diagnostic triad in bronchiectasis" @default.
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- W2024358624 doi "https://doi.org/10.1016/j.ejcdt.2015.03.012" @default.
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