FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024358879> ?p ?o ?g. }

• W2024358879 endingPage "942" @default.
• W2024358879 startingPage "939" @default.
• W2024358879 abstract "The active site of voltage-activated potassium channels is a transmembrane aqueous pore that permits ions to permeate the cell membrane in a rapid yet highly selective manner. A useful probe for the pore of potassium-selective channels is the organic ion tetraethylammonium (TEA), which binds with millimolar affinity to the intracellular opening of the pore and blocks potassium current. In the potassium channel encoded by the Drosophila Shaker gene, an amino acid residue that specifically affects the affinity for intracellular TEA has now been identified by site-directed mutagenesis. This residue is in the middle of a conserved stretch of 18 amino acids that separates two locations that are both near the external opening of the pore. These findings suggest that this conserved region is intimately involved in the formation of the ion conduction pore of voltage-activated potassium channels. Further, a stretch of only eight amino acid residues must traverse 80 percent of the transmembrane electric potential difference." @default.
• W2024358879 created "2016-06-24" @default.
• W2024358879 creator A5021381186 @default.
• W2024358879 creator A5025045433 @default.
• W2024358879 creator A5071835206 @default.
• W2024358879 creator A5080876948 @default.
• W2024358879 date "1991-02-22" @default.
• W2024358879 modified "2023-09-27" @default.
• W2024358879 title "Mutations Affecting Internal TEA Blockade Identify the Probable Pore-Forming Region of a K ⁺ Channel" @default.
• W2024358879 cites W1492664701 @default.
• W2024358879 cites W1966667742 @default.
• W2024358879 cites W1972116208 @default.
• W2024358879 cites W1975038016 @default.
• W2024358879 cites W1979103094 @default.
• W2024358879 cites W1989624644 @default.
• W2024358879 cites W1996071311 @default.
• W2024358879 cites W2006090981 @default.
• W2024358879 cites W2006192148 @default.
• W2024358879 cites W2018126620 @default.
• W2024358879 cites W2025884619 @default.
• W2024358879 cites W2028484749 @default.
• W2024358879 cites W2038321772 @default.
• W2024358879 cites W2042332635 @default.
• W2024358879 cites W2051219862 @default.
• W2024358879 cites W2053967009 @default.
• W2024358879 cites W2080082506 @default.
• W2024358879 cites W2088734315 @default.
• W2024358879 cites W2099975374 @default.
• W2024358879 cites W2131397357 @default.
• W2024358879 cites W2133464980 @default.
• W2024358879 cites W2159513541 @default.
• W2024358879 cites W2398410876 @default.
• W2024358879 cites W2409018897 @default.
• W2024358879 cites W2411186952 @default.
• W2024358879 cites W2885192006 @default.
• W2024358879 cites W4323053696 @default.
• W2024358879 doi "https://doi.org/10.1126/science.2000494" @default.
• W2024358879 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2000494" @default.
• W2024358879 hasPublicationYear "1991" @default.
• W2024358879 type Work @default.
• W2024358879 sameAs 2024358879 @default.
• W2024358879 citedByCount "625" @default.
• W2024358879 countsByYear W20243588792012 @default.
• W2024358879 countsByYear W20243588792013 @default.
• W2024358879 countsByYear W20243588792014 @default.
• W2024358879 countsByYear W20243588792015 @default.
• W2024358879 countsByYear W20243588792016 @default.
• W2024358879 countsByYear W20243588792017 @default.
• W2024358879 countsByYear W20243588792018 @default.
• W2024358879 countsByYear W20243588792019 @default.
• W2024358879 countsByYear W20243588792020 @default.
• W2024358879 countsByYear W20243588792021 @default.
• W2024358879 countsByYear W20243588792022 @default.
• W2024358879 countsByYear W20243588792023 @default.
• W2024358879 crossrefType "journal-article" @default.
• W2024358879 hasAuthorship W2024358879A5021381186 @default.
• W2024358879 hasAuthorship W2024358879A5025045433 @default.
• W2024358879 hasAuthorship W2024358879A5071835206 @default.
• W2024358879 hasAuthorship W2024358879A5080876948 @default.
• W2024358879 hasConcept C118892022 @default.
• W2024358879 hasConcept C121332964 @default.
• W2024358879 hasConcept C12554922 @default.
• W2024358879 hasConcept C170493617 @default.
• W2024358879 hasConcept C178790620 @default.
• W2024358879 hasConcept C181911157 @default.
• W2024358879 hasConcept C185592680 @default.
• W2024358879 hasConcept C198394728 @default.
• W2024358879 hasConcept C24530287 @default.
• W2024358879 hasConcept C2779421379 @default.
• W2024358879 hasConcept C2781295685 @default.
• W2024358879 hasConcept C45516822 @default.
• W2024358879 hasConcept C50254741 @default.
• W2024358879 hasConcept C515207424 @default.
• W2024358879 hasConcept C517785266 @default.
• W2024358879 hasConcept C55493867 @default.
• W2024358879 hasConcept C62520636 @default.
• W2024358879 hasConcept C79879829 @default.
• W2024358879 hasConcept C83743174 @default.
• W2024358879 hasConcept C86803240 @default.
• W2024358879 hasConceptScore W2024358879C118892022 @default.
• W2024358879 hasConceptScore W2024358879C121332964 @default.
• W2024358879 hasConceptScore W2024358879C12554922 @default.
• W2024358879 hasConceptScore W2024358879C170493617 @default.
• W2024358879 hasConceptScore W2024358879C178790620 @default.
• W2024358879 hasConceptScore W2024358879C181911157 @default.
• W2024358879 hasConceptScore W2024358879C185592680 @default.
• W2024358879 hasConceptScore W2024358879C198394728 @default.
• W2024358879 hasConceptScore W2024358879C24530287 @default.
• W2024358879 hasConceptScore W2024358879C2779421379 @default.
• W2024358879 hasConceptScore W2024358879C2781295685 @default.
• W2024358879 hasConceptScore W2024358879C45516822 @default.
• W2024358879 hasConceptScore W2024358879C50254741 @default.
• W2024358879 hasConceptScore W2024358879C515207424 @default.
• W2024358879 hasConceptScore W2024358879C517785266 @default.
• W2024358879 hasConceptScore W2024358879C55493867 @default.
• W2024358879 hasConceptScore W2024358879C62520636 @default.
• W2024358879 hasConceptScore W2024358879C79879829 @default.
• W2024358879 hasConceptScore W2024358879C83743174 @default.

• next