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- W2024363374 abstract "Porcine endothelin (1 nM-0.3 microM) produced a concentration-dependent contraction of the isolated sphincter muscle of the pig iris. Neither atropine (1 microM) nor tetrodotoxin (1 microM) nor pre-exposure of the preparation to 10 microM capsaicin for 15 min affected the endothelin-induced response. We propose that the endothelin-induced contraction of the iris sphincter muscle of the pig is largely due to a direct action on smooth muscle cells and is unrelated to neurogenic myotic mechanisms." @default.
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- W2024363374 date "1989-09-01" @default.
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- W2024363374 title "Contractile effect of endothelin on isolated iris sphincter muscle of the pig" @default.
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- W2024363374 doi "https://doi.org/10.1016/0014-2999(89)90643-2" @default.
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