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- W2024367691 abstract "This review summarizes recent data on the development of non-drosophilid insect transformation systems. The discussion focuses on one particular approach to developing transformation systems that relies on the use of short inverted repeat-type transposable elements analogous to that employed for Drosophila melanogaster transformation. Representatives from four families of short inverted repeat-type transposable elements have been shown to either act as nondrosophilid gene vectors or to have the ability to transpose accurately when introduced into non-host insect cells. Minos, a member of the Tcl family of elements isolated originally from D. hydei has been successfully used as a germline transformation vector in the Medfly, Ceratitis capitata. Hermes, a member of the hAT family of elements isolated originally from Musca domestica has been successfully used as a gene transformation vector in D. melanogaster and has a host range that appears to include culicids. hobo, another member of the hAT family of elements isolated from D. melanogaster also has a broad host range that includes tephritid fruitflies. mariner(Mos), a member of the mariner family of elements isolated from D. mauritiana can transpose in calliphorids. Finally, piggyBac/IFP2, a member of the TTAA-specific family of elements isolated from Trichoplusia ni can transpose when introduced into Spodoptera frugiperda cells. Although routine transformation of insects other than D. melanogaster is not possible it is clear that the raw materials for the development of efficient transformation systems are now available." @default.
- W2024367691 created "2016-06-24" @default.
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- W2024367691 date "1996-09-01" @default.
- W2024367691 modified "2023-10-18" @default.
- W2024367691 title "Transposable elements and gene transformation in non-drosophilid insects" @default.
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- W2024367691 doi "https://doi.org/10.1016/s0965-1748(96)00022-7" @default.
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