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• W2024367984 startingPage "585" @default.
• W2024367984 abstract "The antifreeze glycoproteins (AFGPs) 1 are composed of a repeating tripeptide unit (Ala-Thr-Ala) in which the threonine residue is glycosylated with the disaccharide beta-D-Gal-(1-->3)-alpha-D-GalNAc. A new procedure for synthesizing AFGPs using Fmoc-(Ac4-beta-D-Gal-(1-->3)-benzylidene- alpha-D-GalNAc)Thr-OH (10) as a building block has been developed. Total synthesis of the AFGPs (n = 4, 8) in overall yields of 61% and 33 %, respectively, has demonstrated the usefulness of the method. The synthetic AFGPs 1 (n = 4, 8) showed a similar conformation to the native AFGPs in their circular dichroism spectra." @default.
• W2024367984 created "2016-06-24" @default.
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• W2024367984 date "2001-02-02" @default.
• W2024367984 modified "2023-09-29" @default.
• W2024367984 title "Facile Solid-Phase Synthesis of an Antifreeze Glycoprotein" @default.
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• W2024367984 doi "https://doi.org/10.1002/1521-3765(20010202)7:3<585::aid-chem585>3.0.co;2-6" @default.
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