Matches in SemOpenAlex for { <https://semopenalex.org/work/W2024377992> ?p ?o ?g. }
- W2024377992 endingPage "169" @default.
- W2024377992 startingPage "162" @default.
- W2024377992 abstract "Novel biomimetic amphiphilic chitosan derivative, deoxycholic acid-phosphorylcholine-chitosan conjugate (DCA-PCCs) was synthesized based on the combination of Atherton-Todd reaction for coupling phosphorylcholine (PC) and carbodiimide coupling reaction for linking deoxycholic acid (DCA) to chitosan. The chemical structure of DCA-PCCs was characterized by (1)H and (31)P nuclear magnetic resonance (NMR). The self-assembly of DCA-PCCs in water was analyzed by fluorescence measurements, dynamic laser light-scattering (DLS), zeta potential and transmission electron microscopy (TEM) technologies. The results confirmed that the amphiphilic DCA-PCCs can self-assemble to form nanosized spherical micelles with biomimetic PC shell. In vitro biological evaluation revealed that DCA-PCCs micelles had low toxicity against NIH/3T3 mouse embryonic fibroblasts as well as good hemocompatibility. Using quercetin as a hydrophobic model drug, drug loading and release study suggested that biomimetic DCA-PCCs micelles could be used as a promising nanocarrier avoiding unfavorable biological response for hydrophobic drug delivery applications." @default.
- W2024377992 created "2016-06-24" @default.
- W2024377992 creator A5010336321 @default.
- W2024377992 creator A5013717377 @default.
- W2024377992 creator A5020192167 @default.
- W2024377992 creator A5039229292 @default.
- W2024377992 creator A5051977133 @default.
- W2024377992 creator A5082491573 @default.
- W2024377992 date "2014-12-01" @default.
- W2024377992 modified "2023-10-13" @default.
- W2024377992 title "In vitro drug release and biological evaluation of biomimetic polymeric micelles self-assembled from amphiphilic deoxycholic acid–phosphorylcholine–chitosan conjugate" @default.
- W2024377992 cites W1973459809 @default.
- W2024377992 cites W1975639265 @default.
- W2024377992 cites W1985091983 @default.
- W2024377992 cites W1994572076 @default.
- W2024377992 cites W1998934929 @default.
- W2024377992 cites W2000725843 @default.
- W2024377992 cites W2001983171 @default.
- W2024377992 cites W2002529794 @default.
- W2024377992 cites W2008894627 @default.
- W2024377992 cites W2012611240 @default.
- W2024377992 cites W2014536819 @default.
- W2024377992 cites W2016280060 @default.
- W2024377992 cites W2016676094 @default.
- W2024377992 cites W2021398439 @default.
- W2024377992 cites W2024778839 @default.
- W2024377992 cites W2024928939 @default.
- W2024377992 cites W2043399737 @default.
- W2024377992 cites W2043888626 @default.
- W2024377992 cites W2053426009 @default.
- W2024377992 cites W2058426479 @default.
- W2024377992 cites W2058716233 @default.
- W2024377992 cites W2061093127 @default.
- W2024377992 cites W2075440102 @default.
- W2024377992 cites W2076862348 @default.
- W2024377992 cites W2082456565 @default.
- W2024377992 cites W2088083449 @default.
- W2024377992 cites W2089657872 @default.
- W2024377992 cites W2093587862 @default.
- W2024377992 cites W2104993070 @default.
- W2024377992 cites W2109471598 @default.
- W2024377992 cites W2115824449 @default.
- W2024377992 cites W2120162732 @default.
- W2024377992 cites W2137973045 @default.
- W2024377992 cites W2142829150 @default.
- W2024377992 cites W2171384411 @default.
- W2024377992 cites W2171757680 @default.
- W2024377992 cites W2313363457 @default.
- W2024377992 cites W2330503753 @default.
- W2024377992 doi "https://doi.org/10.1016/j.msec.2014.09.008" @default.
- W2024377992 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25491815" @default.
- W2024377992 hasPublicationYear "2014" @default.
- W2024377992 type Work @default.
- W2024377992 sameAs 2024377992 @default.
- W2024377992 citedByCount "32" @default.
- W2024377992 countsByYear W20243779922015 @default.
- W2024377992 countsByYear W20243779922016 @default.
- W2024377992 countsByYear W20243779922017 @default.
- W2024377992 countsByYear W20243779922018 @default.
- W2024377992 countsByYear W20243779922019 @default.
- W2024377992 countsByYear W20243779922020 @default.
- W2024377992 countsByYear W20243779922021 @default.
- W2024377992 countsByYear W20243779922022 @default.
- W2024377992 countsByYear W20243779922023 @default.
- W2024377992 crossrefType "journal-article" @default.
- W2024377992 hasAuthorship W2024377992A5010336321 @default.
- W2024377992 hasAuthorship W2024377992A5013717377 @default.
- W2024377992 hasAuthorship W2024377992A5020192167 @default.
- W2024377992 hasAuthorship W2024377992A5039229292 @default.
- W2024377992 hasAuthorship W2024377992A5051977133 @default.
- W2024377992 hasAuthorship W2024377992A5082491573 @default.
- W2024377992 hasConcept C11268172 @default.
- W2024377992 hasConcept C134306372 @default.
- W2024377992 hasConcept C155672457 @default.
- W2024377992 hasConcept C15920480 @default.
- W2024377992 hasConcept C171250308 @default.
- W2024377992 hasConcept C178790620 @default.
- W2024377992 hasConcept C18150654 @default.
- W2024377992 hasConcept C184651966 @default.
- W2024377992 hasConcept C185592680 @default.
- W2024377992 hasConcept C192562407 @default.
- W2024377992 hasConcept C197336794 @default.
- W2024377992 hasConcept C2776833585 @default.
- W2024377992 hasConcept C2779399885 @default.
- W2024377992 hasConcept C2779732960 @default.
- W2024377992 hasConcept C2779820397 @default.
- W2024377992 hasConcept C2780749602 @default.
- W2024377992 hasConcept C33923547 @default.
- W2024377992 hasConcept C521977710 @default.
- W2024377992 hasConcept C55493867 @default.
- W2024377992 hasConcept C64237528 @default.
- W2024377992 hasConcept C67407626 @default.
- W2024377992 hasConcept C86181022 @default.
- W2024377992 hasConceptScore W2024377992C11268172 @default.
- W2024377992 hasConceptScore W2024377992C134306372 @default.
- W2024377992 hasConceptScore W2024377992C155672457 @default.
- W2024377992 hasConceptScore W2024377992C15920480 @default.
- W2024377992 hasConceptScore W2024377992C171250308 @default.